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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL329280
Molecular formula	C28H31FN6O
IUPAC name	1-[2-[4-[1-(4-fluorophenyl)-5-(1-methylpyrazol-4-yl)indol-3-yl]piperidin-1-yl]ethyl]imidazolidin-2-one
Molecular weight	486.595
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.4
Synonyms	BDBM50122804 SCHEMBL7203413 1-(2-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-pyrazol-4-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one
Inchi Key	BJICDRUQIDTHQQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H31FN6O/c1-32-18-22(17-31-32)21-2-7-27-25(16-21)26(19-35(27)24-5-3-23(29)4-6-24)20-8-11-33(12-9-20)14-15-34-13-10-30-28(34)36/h2-7,16-20H,8-15H2,1H3,(H,30,36)
PubChem CID	11812916
ChEMBL	CHEMBL329280
IUPHAR	N/A
BindingDB	50122804
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
25130	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
25132	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
25133	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
25131	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
25129	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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