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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2381647
Molecular formula	C8H12N2O4
IUPAC name	(1S,2S,4S,5R,6S)-2,4-diaminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Molecular weight	200.194
Hydrogen bond acceptor	6
Hydrogen bond donor	4
XlogP	-6.7
Synonyms	BDBM50434129 (1S,5R)-4alpha-Amino-2-amino-bicyclo[3.1.0]hexane-2alpha,6alpha-dicarboxylic acid
Inchi Key	BIHSLTSGYFDSHV-FJNNMDBYSA-N
Inchi ID	InChI=1S/C8H12N2O4/c9-2-1-8(10,7(13)14)5-3(2)4(5)6(11)12/h2-5H,1,9-10H2,(H,11,12)(H,13,14)/t2-,3-,4-,5-,8-/m0/s1
PubChem CID	11275666
ChEMBL	CHEMBL2381647
IUPHAR	N/A
BindingDB	50434129
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
24450	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
24449	Metabotropic glutamate receptor 3	Q14832	GRM3	Homo sapiens (Human)	879
24451	Metabotropic glutamate receptor 6	O15303	GRM6	Homo sapiens (Human)	877
24452	Metabotropic glutamate receptor 8	O00222	GRM8	Homo sapiens (Human)	908

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