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Ligand

Namespiropiperidine analogue, 70
Molecular formulaC29H39ClN4O
IUPAC name3-[2-(butylamino)ethyl]-8-(7-chloro-1,2,3,4-tetrahydronaphthalen-1-yl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Molecular weight495.108
Hydrogen bond acceptor4
Hydrogen bond donor1
XlogP5.6
SynonymsCHEMBL516187
BDBM26952
3-[2-(butylamino)ethyl]-8-(7-chloro-1,2,3,4-tetrahydronaphthalen-1-yl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Inchi KeyBEBLFDYTZHKBFQ-UHFFFAOYSA-N
Inchi IDInChI=1S/C29H39ClN4O/c1-2-3-16-31-17-20-33-22-34(25-9-5-4-6-10-25)29(28(33)35)14-18-32(19-15-29)27-11-7-8-23-12-13-24(30)21-26(23)27/h4-6,9-10,12-13,21,27,31H,2-3,7-8,11,14-20,22H2,1H3
PubChem CID25190627
ChEMBLCHEMBL516187
IUPHARN/A
BindingDB26952
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand has a partition coefficient log P greater than 5.

Known GPCRs

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Total entries: 4
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
21418Delta-type opioid receptorP41143OPRD1Homo sapiens (Human)372
21421Kappa-type opioid receptorP41145OPRK1Homo sapiens (Human)380
21419Mu-type opioid receptorP35372OPRM1Homo sapiens (Human)400
21420Nociceptin receptorP41146OPRL1Homo sapiens (Human)370

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