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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	spiropiperidine analogue, 18
Molecular formula	C29H29N3O
IUPAC name	8-benzhydryl-1-phenyl-3-prop-2-ynyl-1,3,8-triazaspiro[4.5]decan-4-one
Molecular weight	435.571
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	5.1
Synonyms	CHEMBL474708 BDBM26897 8-(diphenylmethyl)-1-phenyl-3-(prop-2-yn-1-yl)-1,3,8-triazaspiro[4.5]decan-4-one
Inchi Key	BCFWMJUOTGHXSO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H29N3O/c1-2-20-31-23-32(26-16-10-5-11-17-26)29(28(31)33)18-21-30(22-19-29)27(24-12-6-3-7-13-24)25-14-8-4-9-15-25/h1,3-17,27H,18-23H2
PubChem CID	25190578
ChEMBL	CHEMBL474708
IUPHAR	N/A
BindingDB	26897
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
20140	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
20142	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
20141	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400
20139	Nociceptin receptor	P41146	OPRL1	Homo sapiens (Human)	370

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