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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL512612
Molecular formula	C28H28Cl2N2O2
IUPAC name	8-[bis(2-chlorophenyl)methyl]-3-(4-methoxyphenyl)-8-azabicyclo[3.2.1]octane-3-carboxamide
Molecular weight	495.444
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	6.2
Synonyms	8-(bis(2-chlorophenyl)methyl)-3-(4-methoxyphenyl)-8-azabicyclo[3.2.1]octane-3-carboxamide BDBM50259351
Inchi Key	AXRTXOCKWKDAKF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H28Cl2N2O2/c1-34-21-14-10-18(11-15-21)28(27(31)33)16-19-12-13-20(17-28)32(19)26(22-6-2-4-8-24(22)29)23-7-3-5-9-25(23)30/h2-11,14-15,19-20,26H,12-13,16-17H2,1H3,(H2,31,33)
PubChem CID	44574850
ChEMBL	CHEMBL512612
IUPHAR	N/A
BindingDB	50259351
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
17015	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400
17016	Nociceptin receptor	P41146	OPRL1	Homo sapiens (Human)	370

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