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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL274489
Molecular formula	C27H30N4O5S
IUPAC name	N-[2-[2-[(4,5-dimethyl-1,2-oxazol-3-yl)sulfamoyl]phenyl]-5-(1,3-oxazol-2-yl)phenyl]-N,3,3-trimethylbutanamide
Molecular weight	522.62
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	4.7
Synonyms	BDBM50122676 N-[2''-(4,5-Dimethyl-isoxazol-3-ylsulfamoyl)-4-oxazol-2-yl-biphenyl-2-yl]-3,3,N-trimethyl-butyramide
Inchi Key	AXFKGEZDVMCYEO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H30N4O5S/c1-17-18(2)36-29-25(17)30-37(33,34)23-10-8-7-9-21(23)20-12-11-19(26-28-13-14-35-26)15-22(20)31(6)24(32)16-27(3,4)5/h7-15H,16H2,1-6H3,(H,29,30)
PubChem CID	44277840
ChEMBL	CHEMBL274489
IUPHAR	N/A
BindingDB	50122676
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
16661	Endothelin receptor type B	P24530	EDNRB	Homo sapiens (Human)	442
16660	Endothelin-1 receptor	P25101	EDNRA	Homo sapiens (Human)	427

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