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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2059306
Molecular formula	C24H28N4O2
IUPAC name	1-[3-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Molecular weight	404.514
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	3.8
Synonyms	BDBM50388671
Inchi Key	AXDIUCNCCQGFAR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H28N4O2/c29-23-11-10-18-6-1-3-8-21(18)27(23)15-5-14-26-16-12-19(13-17-26)28-22-9-4-2-7-20(22)25-24(28)30/h1-4,6-9,19H,5,10-17H2,(H,25,30)
PubChem CID	62707610
ChEMBL	CHEMBL2059306
IUPHAR	N/A
BindingDB	50388671
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
16575	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
16576	Muscarinic acetylcholine receptor M1	P11229	CHRM1	Homo sapiens (Human)	460
442304	Muscarinic acetylcholine receptor M2	P08172	CHRM2	Homo sapiens (Human)	466
442306	Muscarinic acetylcholine receptor M3	P20309	CHRM3	Homo sapiens (Human)	590
16574	Muscarinic acetylcholine receptor M4	P08173	CHRM4	Homo sapiens (Human)	479
442305	Muscarinic acetylcholine receptor M5	P08912	CHRM5	Homo sapiens (Human)	532

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