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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL234829
Molecular formula	C27H27F3N2OS
IUPAC name	2,6-dimethyl-4-[[4-[[2-(trifluoromethyl)phenothiazin-10-yl]methyl]phenyl]methyl]morpholine
Molecular weight	484.581
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	6.5
Synonyms	N/A
Inchi Key	AWVOBGFKVYPFBL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H27F3N2OS/c1-18-14-31(15-19(2)33-18)16-20-7-9-21(10-8-20)17-32-23-5-3-4-6-25(23)34-26-12-11-22(13-24(26)32)27(28,29)30/h3-13,18-19H,14-17H2,1-2H3
PubChem CID	44431661
ChEMBL	CHEMBL234829
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
442300	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
16401	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
16402	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
16399	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
16398	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
16400	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400

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