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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL233749
Molecular formula	C25H26Cl2N2O
IUPAC name	4-[2-(aminomethyl)phenyl]-1-[bis(4-chlorophenyl)methyl]piperidin-4-ol
Molecular weight	441.396
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	4.7
Synonyms	4-(2-(aminomethyl)phenyl)-1-(bis(4-chlorophenyl)methyl)piperidin-4-ol BDBM50210215
Inchi Key	ASFBQTPLOUDQLA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H26Cl2N2O/c26-21-9-5-18(6-10-21)24(19-7-11-22(27)12-8-19)29-15-13-25(30,14-16-29)23-4-2-1-3-20(23)17-28/h1-12,24,30H,13-17,28H2
PubChem CID	44430046
ChEMBL	CHEMBL233749
IUPHAR	N/A
BindingDB	50210215
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
13086	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
13085	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
13087	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400
13084	Nociceptin receptor	P41146	OPRL1	Homo sapiens (Human)	370

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