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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS001223940
Molecular formula	C18H21FN2S
IUPAC name	1-[1-(2,4-dimethylphenyl)ethyl]-3-[(4-fluorophenyl)methyl]thiourea
Molecular weight	316.438
Hydrogen bond acceptor	2
Hydrogen bond donor	2
XlogP	4.2
Synonyms	AKOS022156752 ST50838635 HMS2974M06 1-[1-(2,4-dimethylphenyl)ethyl]-3-(4-fluorobenzyl)thiourea MolPort-008-307-760 STK493859 MCULE-3842814387 AKOS003345641 SMR000678366 CHEMBL1383859 {[(2,4-dimethylphenyl)ethyl]amino}{[(4-fluorophenyl)methyl]amino}methane-1-thi one [ Show all ]
Inchi Key	ARIGVURYRMAIFM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H21FN2S/c1-12-4-9-17(13(2)10-12)14(3)21-18(22)20-11-15-5-7-16(19)8-6-15/h4-10,14H,11H2,1-3H3,(H2,20,21,22)
PubChem CID	17263474
ChEMBL	CHEMBL1383859
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
12501	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
12502	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
464374	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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