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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL477821
Molecular formula	C24H29ClN4O
IUPAC name	3-[1-[1-[(2-chlorophenyl)methyl]piperidin-4-yl]piperidin-4-yl]-1H-benzimidazol-2-one
Molecular weight	424.973
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	4.1
Synonyms	BDBM50263372 SCHEMBL5476466 1-[1''-(2-Chloro-benzyl)-[1,4'']bipiperidinyl-4-yl]-1,3-dihydro-benzoimidazol-2-one
Inchi Key	AQMPTYUVSBXZPZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H29ClN4O/c25-21-6-2-1-5-18(21)17-27-13-9-19(10-14-27)28-15-11-20(12-16-28)29-23-8-4-3-7-22(23)26-24(29)30/h1-8,19-20H,9-17H2,(H,26,30)
PubChem CID	10251795
ChEMBL	CHEMBL477821
IUPHAR	N/A
BindingDB	50263372
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
11916	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
11915	Muscarinic acetylcholine receptor M1	P11229	CHRM1	Homo sapiens (Human)	460
11917	Muscarinic acetylcholine receptor M2	P08172	CHRM2	Homo sapiens (Human)	466
11919	Muscarinic acetylcholine receptor M3	P20309	CHRM3	Homo sapiens (Human)	590
11918	Muscarinic acetylcholine receptor M4	P08173	CHRM4	Homo sapiens (Human)	479
11914	Muscarinic acetylcholine receptor M5	P08912	CHRM5	Homo sapiens (Human)	532

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