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Ligand

Namespiropiperidine analogue, 36
Molecular formulaC35H42Cl2N4O
IUPAC name8-[bis(2-chlorophenyl)methyl]-3-[2-(cyclohexylmethylamino)ethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Molecular weight605.648
Hydrogen bond acceptor4
Hydrogen bond donor1
XlogP8.2
SynonymsBDBM26915
8-[bis(2-chlorophenyl)methyl]-3-{2-[(cyclohexylmethyl)amino]ethyl}-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
CHEMBL501088
Inchi KeyAQGQQVZAISJFLE-UHFFFAOYSA-N
Inchi IDInChI=1S/C35H42Cl2N4O/c36-31-17-9-7-15-29(31)33(30-16-8-10-18-32(30)37)39-22-19-35(20-23-39)34(42)40(26-41(35)28-13-5-2-6-14-28)24-21-38-25-27-11-3-1-4-12-27/h2,5-10,13-18,27,33,38H,1,3-4,11-12,19-26H2
PubChem CID25190595
ChEMBLCHEMBL501088
IUPHARN/A
BindingDB26915
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand is heavier than 500 daltons.
This ligand has a partition coefficient log P greater than 5.

Known GPCRs

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Total entries: 4
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
11682Delta-type opioid receptorP41143OPRD1Homo sapiens (Human)372
11683Kappa-type opioid receptorP41145OPRK1Homo sapiens (Human)380
11685Mu-type opioid receptorP35372OPRM1Homo sapiens (Human)400
11684Nociceptin receptorP41146OPRL1Homo sapiens (Human)370

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