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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL18303
Molecular formula	C16H21N5
IUPAC name	N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2-(2-propan-2-ylpyrazol-3-yl)aniline
Molecular weight	283.379
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	1.6
Synonyms	SCHEMBL6368405 BDBM50222925 N-(1-Imidazoline-2-ylmethyl)-2-(1-isopropyl-1H-pyrazole-5-yl)aniline
Inchi Key	APTMFOIALVJASZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H21N5/c1-12(2)21-15(7-8-20-21)13-5-3-4-6-14(13)19-11-16-17-9-10-18-16/h3-8,12,19H,9-11H2,1-2H3,(H,17,18)
PubChem CID	22493387
ChEMBL	CHEMBL18303
IUPHAR	N/A
BindingDB	50222925
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
11355	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
11356	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
11357	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572

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