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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000713029
Molecular formula	C18H23N3O3
IUPAC name	(Z)-2-cyano-N-cyclohexyl-3-(5-morpholin-4-ylfuran-2-yl)prop-2-enamide
Molecular weight	329.4
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.1
Synonyms	(Z)-2-cyano-N-cyclohexyl-3-(5-morpholino-2-furyl)acrylamide CHEMBL1421228 AC1LIDPM BDBM60144 SR-01000314401-1 (Z)-2-cyano-N-cyclohexyl-3-[5-(4-morpholinyl)-2-furanyl]-2-propenamide cid_929419 AKOS000627082 SMR000282796 (Z)-2-cyano-N-cyclohexyl-3-(5-morpholin-4-ylfuran-2-yl)prop-2-enamide ZINC520049 2-Cyano-N-cyclohexyl-3-(5-morpholin-4-yl-furan-2-yl)-acrylamide HMS2682C14 BAS 01567106 SR-01000314401 [ Show all ]
Inchi Key	APSOMBILXZWHQR-OWBHPGMISA-N
Inchi ID	InChI=1S/C18H23N3O3/c19-13-14(18(22)20-15-4-2-1-3-5-15)12-16-6-7-17(24-16)21-8-10-23-11-9-21/h6-7,12,15H,1-5,8-11H2,(H,20,22)/b14-12-
PubChem CID	929419
ChEMBL	CHEMBL1421228
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
464255	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593
11299	Thyrotropin-releasing hormone receptor	P34981	TRHR	Homo sapiens (Human)	398

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