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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3358498
Molecular formula	C24H27FN4O
IUPAC name	N-[4-[4-(3-fluorophenyl)piperazin-1-yl]butyl]isoquinoline-3-carboxamide
Molecular weight	406.505
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.2
Synonyms	BDBM50031360
Inchi Key	AJIGPZIDDACLTM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H27FN4O/c25-21-8-5-9-22(17-21)29-14-12-28(13-15-29)11-4-3-10-26-24(30)23-16-19-6-1-2-7-20(19)18-27-23/h1-2,5-9,16-18H,3-4,10-15H2,(H,26,30)
PubChem CID	118722913
ChEMBL	CHEMBL3358498
IUPHAR	N/A
BindingDB	50031360
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
441973	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
441976	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
441975	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
441974	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
441972	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400

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