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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL80230
Molecular formula	C24H23N3O3
IUPAC name	7-[4-[(4-hydroxy-3-phenylphenyl)methyl]piperazin-1-yl]-3H-1,3-benzoxazol-2-one
Molecular weight	401.466
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	3.8
Synonyms	7-[4-(6-Hydroxy-biphenyl-3-ylmethyl)-piperazin-1-yl]-3H-benzooxazol-2-one BDBM50103826 7-[4-(6-Hydroxy-3-biphenylylmethyl)piperazino]-2,3-dihydrobenzoxazole-2-one
Inchi Key	AIPVMDNBQLPSHM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H23N3O3/c28-22-10-9-17(15-19(22)18-5-2-1-3-6-18)16-26-11-13-27(14-12-26)21-8-4-7-20-23(21)30-24(29)25-20/h1-10,15,28H,11-14,16H2,(H,25,29)
PubChem CID	44315406
ChEMBL	CHEMBL80230
IUPHAR	N/A
BindingDB	50103826
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
6436	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
6435	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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