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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL70924
Molecular formula	C30H34N6O6S
IUPAC name	1-[2-[6-[(4-tert-butylphenyl)sulfonylamino]-5-(2-methoxyphenoxy)-2-methylpyrimidin-4-yl]oxyethyl]-3-pyridin-2-ylurea
Molecular weight	606.698
Hydrogen bond acceptor	10
Hydrogen bond donor	3
XlogP	4.9
Synonyms	BDBM50290058 SCHEMBL8322960 4-tert-Butyl-N-{5-(2-methoxy-phenoxy)-2-methyl-6-[2-(3-pyridin-2-yl-ureido)-ethoxy]-pyrimidin-4-yl}-benzenesulfonamide
Inchi Key	AHRRXSCSEHTVQL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C30H34N6O6S/c1-20-33-27(36-43(38,39)22-15-13-21(14-16-22)30(2,3)4)26(42-24-11-7-6-10-23(24)40-5)28(34-20)41-19-18-32-29(37)35-25-12-8-9-17-31-25/h6-17H,18-19H2,1-5H3,(H,33,34,36)(H2,31,32,35,37)
PubChem CID	19432672
ChEMBL	CHEMBL70924
IUPHAR	N/A
BindingDB	50290058
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
5831	Endothelin receptor type B	P24530	EDNRB	Homo sapiens (Human)	442
5830	Endothelin-1 receptor	P25101	EDNRA	Homo sapiens (Human)	427

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