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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3128185
Molecular formula	C30H29FN4O2S
IUPAC name	(4R)-2-(4-fluorophenyl)-N-[4-[[(2S,5R)-5-[(R)-hydroxy(pyridin-3-yl)methyl]pyrrolidin-2-yl]methyl]phenyl]-5,6-dihydro-4H-cyclopenta[d][1,3]thiazole-4-carboxamide
Molecular weight	528.646
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	4.2
Synonyms	N/A
Inchi Key	AHGPIPADZZLPDD-XVOBZGQLSA-N
Inchi ID	InChI=1S/C30H29FN4O2S/c31-21-7-5-19(6-8-21)30-35-27-24(12-14-26(27)38-30)29(37)34-22-9-3-18(4-10-22)16-23-11-13-25(33-23)28(36)20-2-1-15-32-17-20/h1-10,15,17,23-25,28,33,36H,11-14,16H2,(H,34,37)/t23-,24+,25+,28+/m0/s1
PubChem CID	76332892
ChEMBL	CHEMBL3128185
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
5527	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
5526	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
5528	Beta-3 adrenergic receptor	P13945	ADRB3	Homo sapiens (Human)	408

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