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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL220521
Molecular formula	C12H13ClN2O2
IUPAC name	(10bR)-10-chloro-7-methoxy-2,3,4,10b-tetrahydro-1H-pyrazino[1,2-b]isoindol-6-one
Molecular weight	252.698
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	0.9
Synonyms	BDBM50205885 SCHEMBL13119133 ((R)-10-chloro-7-methoxy-1,3,4,10b-tetrahydropyrazino[2,1-a]isoindol-6(2 H)-one
Inchi Key	AGSBXAJKEQTLFT-QMMMGPOBSA-N
Inchi ID	InChI=1S/C12H13ClN2O2/c1-17-9-3-2-7(13)10-8-6-14-4-5-15(8)12(16)11(9)10/h2-3,8,14H,4-6H2,1H3/t8-/m0/s1
PubChem CID	16115390
ChEMBL	CHEMBL220521
IUPHAR	N/A
BindingDB	50205885
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
5164	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
5162	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
5163	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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