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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL118188
Molecular formula	C23H24FN3O3
IUPAC name	5-[(E)-[3-(4-fluorophenyl)-2-imidazol-1-yl-1-phenylpropylidene]amino]oxypentanoic acid
Molecular weight	409.461
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	4.4
Synonyms	SCHEMBL9423399 5-[3-(4-Fluoro-phenyl)-2-imidazol-1-yl-1-phenyl-prop-(E)-ylideneaminooxy]-pentanoic acid BDBM50037766 L008111 5-[[[(Z)-1-Phenyl-2-(1H-imidazol-1-yl)-3-(4-fluorophenyl)propylidene]amino]oxy]pentanoic acid
Inchi Key	AFEOYNXQWALUNY-WNAAXNPUSA-N
Inchi ID	InChI=1S/C23H24FN3O3/c24-20-11-9-18(10-12-20)16-21(27-14-13-25-17-27)23(19-6-2-1-3-7-19)26-30-15-5-4-8-22(28)29/h1-3,6-7,9-14,17,21H,4-5,8,15-16H2,(H,28,29)/b26-23+
PubChem CID	10092922
ChEMBL	CHEMBL118188
IUPHAR	N/A
BindingDB	50037766
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
4106	Thromboxane A2 receptor	P21731	TBXA2R	Homo sapiens (Human)	343

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