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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3597637
Molecular formula	C25H29ClN4O2
IUPAC name	N-[4-[4-(3-chloro-2-methoxyphenyl)piperazin-1-yl]butyl]quinoline-3-carboxamide
Molecular weight	452.983
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.4
Synonyms	BDBM50104922
Inchi Key	AENWLGXTORARIE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H29ClN4O2/c1-32-24-21(26)8-6-10-23(24)30-15-13-29(14-16-30)12-5-4-11-27-25(31)20-17-19-7-2-3-9-22(19)28-18-20/h2-3,6-10,17-18H,4-5,11-16H2,1H3,(H,27,31)
PubChem CID	122183765
ChEMBL	CHEMBL3597637
IUPHAR	N/A
BindingDB	50104922
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
463331	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
463332	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
463333	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
463329	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
463330	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400

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