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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000544661
Molecular formula	C18H12Br2N4
IUPAC name	2,4-bis(3-bromophenyl)-7-methylpyrazolo[3,4-d]pyridazine
Molecular weight	444.13
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	4.6
Synonyms	AC1LO5OX SMR000164076 2,4-bis(3-bromophenyl)-7-methylpyrazolo[3,4-d]pyridazine AJ-916/40989363 ZINC988040 2,4-bis(3-bromophenyl)-7-methyl-2H-pyrazolo[3,4-d]pyridazine CHEMBL1536422 MolPort-002-817-998 BDBM88589 2,4-bis(3-bromophenyl)-7-methyl-pyrazolo[3,4-d]pyridazine cid_1214669 [ Show all ]
Inchi Key	AECFCCDRHPPLMX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H12Br2N4/c1-11-17-16(10-24(23-17)15-7-3-6-14(20)9-15)18(22-21-11)12-4-2-5-13(19)8-12/h2-10H,1H3
PubChem CID	1214669
ChEMBL	CHEMBL1536422
IUPHAR	N/A
BindingDB	88589
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
3337	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
3338	Melanocortin receptor 4	P32245	MC4R	Homo sapiens (Human)	332
3339	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371

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