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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1734241
Molecular formula	C18H19F3N4O4S2
IUPAC name	2-[[2-[4-[2-(trifluoromethyl)phenyl]sulfonylpiperazin-1-yl]acetyl]amino]thiophene-3-carboxamide
Molecular weight	476.489
Hydrogen bond acceptor	10
Hydrogen bond donor	2
XlogP	2.1
Synonyms	ZINC35963748 2-(2-{4-[2-(trifluoromethyl)benzenesulfonyl]piperazin-1-yl}acetamido)thiophene-3-carboxamide MLS002166283 BDBM50342351 SMR001248633 HMS3053F09 870698-01-4 MolPort-005-325-151 Z31017859 2-(2-(4-(2-(trifluoromethyl)phenylsulfonyl)piperazin-1-yl)acetamido)thiophene-3-carboxamide MCULE-7093763854 AKOS034150207 NCGC00241095-01 [ Show all ]
Inchi Key	AAAZRMGPBSWFDK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H19F3N4O4S2/c19-18(20,21)13-3-1-2-4-14(13)31(28,29)25-8-6-24(7-9-25)11-15(26)23-17-12(16(22)27)5-10-30-17/h1-5,10H,6-9,11H2,(H2,22,27)(H,23,26)
PubChem CID	16231644
ChEMBL	CHEMBL1734241
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
22	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
462975	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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