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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000082495
Molecular formula	C23H24N4O3
IUPAC name	1-benzyl-3-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]pyrrolidine-2,5-dione
Molecular weight	404.47
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	1.9
Synonyms	AKOS022086089 STK174748 1-benzyl-3-[4-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidin-1-yl]pyrrolidine-2,5-dione HMS2275B23 AC1MG984 MLS002548684 SR-01000300180 1-benzyl-3-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]pyrrolidine-2,5-dione MCULE-6604945396 AKOS003337025 MolPort-001-605-120 1-benzyl-3-[4-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)-1-piperidinyl]-2,5-pyrrolidinedione CHEMBL1478935 SR-01000300180-1 A3746/0158788 MLS000052729 [ Show all ]
Inchi Key	AAAWRDCWFBVNLC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H24N4O3/c28-21-14-20(22(29)26(21)15-16-6-2-1-3-7-16)25-12-10-17(11-13-25)27-19-9-5-4-8-18(19)24-23(27)30/h1-9,17,20H,10-15H2,(H,24,30)
PubChem CID	2982527
ChEMBL	CHEMBL1478935
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
20	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
462974	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593
21	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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