You can:
| Name | Substance-P receptor |
|---|---|
| Species | Meriones unguiculatus (Mongolian jird) |
| Gene | TACR1 |
| Synonym | NK-1 receptor NK-1R SPR Tachykinin receptor 1 |
| Disease | N/A for non-human GPCRs |
| Length | 407 |
| Amino acid sequence | MDNVLPGDSDLFPNISTNSSESNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVVIFVIWVLALLLAFPQGYYSTTETMPGRVVCMIEWPEHPNRTYEKAYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHVFFLLPYINPDLYVKKFIQQVYLAIMWLAMSSTMYNPIIYCCLNDRFRLGFKHAFRCCPFISAGDYEGLEMKSTRYLQTQGSVYKVSRLETTISTVVGAHEDEAEEGPKATPSSLDLTSNGSSRSNSKTMTESSSFYSNMLA |
| UniProt | Q5DUB1 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL1764942 |
| IUPHAR | N/A |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 463458 |  CHEMBL3596492 | C28H27F3N2O | 464.532 | 6 / 0 | 6.1 | No |
| 464535 |  Aprepitant | C23H21F7N4O3 | 534.435 | 12 / 2 | 4.2 | No |
| 465021 |  CHEMBL3596478 | C28H31F3N2O | 468.564 | 6 / 1 | 6.0 | No |
| 465753 |  CHEMBL3596474 | C26H25ClF3NO | 459.937 | 5 / 1 | 6.5 | No |
| 468358 |  CHEMBL3596483 | C27H25F3N2O | 450.505 | 6 / 1 | 5.6 | No |
| 469121 |  SCHEMBL5446697 | C22H27N5O2 | 393.491 | 6 / 1 | 3.1 | Yes |
| 471856 |  CHEMBL3596447 | C21H25N5O2 | 379.464 | 6 / 1 | 2.9 | Yes |
| 472133 |  CHEMBL3596451 | C22H21F6N5O | 485.434 | 11 / 1 | 4.5 | No |
| 475066 |  CHEMBL3596462 | C26H25F4NO | 443.486 | 6 / 1 | 6.0 | No |
| 475708 |  CHEMBL3596475 | C28H28F3NO3 | 483.531 | 7 / 1 | 5.8 | No |
| 476418 |  CHEMBL3596496 | C34H31F3N2O | 540.63 | 6 / 0 | 7.6 | No |
| 477089 |  CHEMBL3596459 | C30H28F3NO | 475.555 | 5 / 1 | 7.1 | No |
| 477615 |  CHEMBL3596493 | C29H29F3N2O | 478.559 | 6 / 0 | 6.5 | No |
| 477641 |  CHEMBL3596465 | C27H28F3NO2 | 455.521 | 6 / 1 | 5.9 | No |
| 479075 |  CHEMBL3596467 | C27H25F3N2O | 450.505 | 6 / 1 | 5.6 | No |
| 479110 |  CHEMBL3596479 | C26H25F3N2O3 | 470.492 | 7 / 1 | 5.7 | No |
| 479751 |  CHEMBL3596494 | C30H31F3N2O | 492.586 | 6 / 0 | 6.9 | No |
| 479827 |  SCHEMBL3597978 | C22H24F3N5O | 431.463 | 8 / 1 | 4.0 | Yes |
| 481020 |  CHEMBL3596482 | C27H28F3NO2 | 455.521 | 6 / 1 | 5.9 | No |
| 481669 |  CHEMBL3596471 | C26H26F3NO2 | 441.494 | 6 / 2 | 5.5 | No |
| 481721 |  CHEMBL3596473 | C27H25F6NO | 493.493 | 8 / 1 | 6.8 | No |
| 481739 |  CHEMBL3596495 | C30H29F3N2O | 490.57 | 6 / 0 | 6.6 | No |
| 482538 |  CHEMBL3596476 | C26H25F4NO | 443.486 | 6 / 1 | 6.0 | No |
| 483697 |  CHEMBL3596470 | C26H25F3N2O3 | 470.492 | 7 / 1 | 5.7 | No |
| 485325 |  CHEMBL3596490 | C26H24F3N3O | 451.493 | 7 / 1 | 4.6 | Yes |
| 485584 |  CHEMBL3596486 | C27H23F5N2O | 486.486 | 8 / 1 | 5.8 | No |
| 488661 |  SCHEMBL3591663 | C25H25F3N2O | 426.483 | 6 / 1 | 4.9 | Yes |
| 489990 |  CHEMBL3596448 | C21H22F3N5O2 | 433.435 | 9 / 1 | 3.4 | Yes |
| 234472 |  NKP608 | C31H24ClF6N3O2 | 619.992 | 9 / 1 | 7.6 | No |
| 494307 |  CHEMBL3596463 | C27H28F3NO | 439.522 | 5 / 1 | 6.3 | No |
| 496010 |  CHEMBL3596477 | C27H28F3NO | 439.522 | 5 / 1 | 6.3 | No |
| 496163 |  CHEMBL3596461 | C26H25ClF3NO | 459.937 | 5 / 1 | 6.5 | No |
| 496324 |  CHEMBL3596466 | C27H28F3NO | 439.522 | 5 / 1 | 6.3 | No |
| 499325 |  CHEMBL3596484 | C27H24F4N2O | 468.496 | 7 / 1 | 5.7 | No |
| 502080 |  CHEMBL3596480 | C28H30F3NO2 | 469.548 | 6 / 1 | 6.2 | No |
| 502601 |  CHEMBL3596455 | C26H26F3NO | 425.495 | 5 / 1 | 5.9 | No |
| 502649 |  CHEMBL3596460 | C30H28F3NO | 475.555 | 5 / 1 | 7.1 | No |
| 502801 |  CHEMBL3596457 | C24H24F3NO2 | 415.456 | 6 / 1 | 5.0 | Yes |
| 503095 |  CHEMBL3596458 | C23H23F3N2OS | 432.505 | 7 / 1 | 5.0 | Yes |
| 503379 |  CHEMBL3596491 | C26H24F3N3O | 451.493 | 7 / 1 | 4.9 | Yes |
| 504281 |  CHEMBL3596446 | C20H23N5O2 | 365.437 | 6 / 1 | 2.5 | Yes |
| 504619 |  CHEMBL3596487 | C27H21F7N2O | 522.467 | 10 / 1 | 6.0 | No |
| 506146 |  CHEMBL3596452 | C21H22F3N5O | 417.436 | 8 / 2 | 3.5 | Yes |
| 506196 |  CHEMBL3596454 | C22H24F3N5O | 431.463 | 8 / 1 | 4.1 | Yes |
| 506959 |  CHEMBL3596485 | C27H23F5N2O | 486.486 | 8 / 1 | 5.8 | No |
| 507844 |  CHEMBL3596488 | C27H24ClF3N2O | 484.947 | 6 / 1 | 6.2 | No |
| 508320 |  CHEMBL3596469 | C26H27F3N2O | 440.51 | 6 / 2 | 5.2 | No |
| 509207 |  CHEMBL3596472 | C27H26F3NO3 | 469.504 | 7 / 1 | 5.7 | No |
| 509263 |  CHEMBL3596464 | C26H25F3N2O3 | 470.492 | 7 / 1 | 5.7 | No |
| 509299 |  CHEMBL3596468 | C26H25F4NO | 443.486 | 6 / 1 | 6.0 | No |
| 509365 |  CHEMBL3596489 | C28H27F3N2O | 464.532 | 6 / 1 | 6.0 | No |
| 402633 |  Orvepitant | C31H35F7N4O2 | 628.636 | 10 / 0 | 5.4 | No |
| 513046 |  CHEMBL3596453 | C22H24F3N5O | 431.463 | 8 / 1 | 3.6 | Yes |
| 515480 |  CHEMBL3596481 | C26H26F3NO2 | 441.494 | 6 / 2 | 5.5 | No |
| 515636 |  SCHEMBL3599336 | C25H25F3N2O | 426.483 | 6 / 1 | 4.8 | Yes |
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