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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3596493
Molecular formula	C29H29F3N2O
IUPAC name	4-[3-[(1-ethyl-4-phenylpiperidin-4-yl)methoxymethyl]-5-(trifluoromethyl)phenyl]benzonitrile
Molecular weight	478.559
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	6.5
Synonyms	BDBM50106366 HNLCQMZJSHLFJU-UHFFFAOYSA-N 3'-(((1-Ethyl-4-phenylpiperidin-4-yl)methoxy)methyl)-5'-(trifluoromethyl)biphenyl-4-carbonitrile SCHEMBL3586664
Inchi Key	HNLCQMZJSHLFJU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H29F3N2O/c1-2-34-14-12-28(13-15-34,26-6-4-3-5-7-26)21-35-20-23-16-25(18-27(17-23)29(30,31)32)24-10-8-22(19-33)9-11-24/h3-11,16-18H,2,12-15,20-21H2,1H3
PubChem CID	58993578
ChEMBL	CHEMBL3596493
IUPHAR	N/A
BindingDB	50106366
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
477615	Substance-P receptor	Q5DUB1	TACR1	Meriones unguiculatus (Mongolian jird)	407
561013	Substance-P receptor	P14600	Tacr1	Rattus norvegicus (Rat)	407

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