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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3596451
Molecular formula	C22H21F6N5O
IUPAC name	4-phenyl-4-[[3-(trifluoromethyl)-5-[5-(trifluoromethyl)tetrazol-1-yl]phenyl]methoxymethyl]piperidine
Molecular weight	485.434
Hydrogen bond acceptor	11
Hydrogen bond donor	1
XlogP	4.5
Synonyms	BDBM50108632 FCEHSHIDOMJCPN-UHFFFAOYSA-N 4-Phenyl-4-((3-(trifluoromethyl)-5-(5-(trifluoromethyl)-1H-tetrazol-1-yl)benzyloxy)methyl)piperidine SCHEMBL5446528
Inchi Key	FCEHSHIDOMJCPN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H21F6N5O/c23-21(24,25)17-10-15(11-18(12-17)33-19(22(26,27)28)30-31-32-33)13-34-14-20(6-8-29-9-7-20)16-4-2-1-3-5-16/h1-5,10-12,29H,6-9,13-14H2
PubChem CID	24785445
ChEMBL	CHEMBL3596451
IUPHAR	N/A
BindingDB	50108632
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
472133	Substance-P receptor	Q5DUB1	TACR1	Meriones unguiculatus (Mongolian jird)	407
559619	Substance-P receptor	P14600	Tacr1	Rattus norvegicus (Rat)	407

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