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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3596452
Molecular formula	C21H22F3N5O
IUPAC name	4-phenyl-4-[[3-(2H-tetrazol-5-yl)-5-(trifluoromethyl)phenyl]methoxymethyl]piperidine
Molecular weight	417.436
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	3.5
Synonyms	BDBM50108633 SCHEMBL3594895 4-((3-(1H-Tetrazol-5-yl)-5-(trifluoromethyl)benzyloxy)methyl)-4-phenylpiperidine UZKYNGFCRNTQPY-UHFFFAOYSA-N
Inchi Key	UZKYNGFCRNTQPY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H22F3N5O/c22-21(23,24)18-11-15(10-16(12-18)19-26-28-29-27-19)13-30-14-20(6-8-25-9-7-20)17-4-2-1-3-5-17/h1-5,10-12,25H,6-9,13-14H2,(H,26,27,28,29)
PubChem CID	58993596
ChEMBL	CHEMBL3596452
IUPHAR	N/A
BindingDB	50108633
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
506146	Substance-P receptor	Q5DUB1	TACR1	Meriones unguiculatus (Mongolian jird)	407
568219	Substance-P receptor	P14600	Tacr1	Rattus norvegicus (Rat)	407

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