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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
Download all results in tab-seperated text for 903398 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    18001 1haz:B (1.4) BS01 peptide 3.4.21.36 GO:0004252 ... P00772 11473259
    18002 1haz:B (1.4) BS02 CA 3.4.21.36 GO:0004252 ... P00772 11473259
    18003 1hb0:B (2.05) BS01 CA 3.4.21.36 GO:0004252 ... P00772 11473259
    18004 1hb1:A (1.55) BS01 OCV 1.21.3.1 GO:0005506 ... P05326 11755401
    18005 1hb1:A (1.55) BS02 FE2 1.21.3.1 GO:0005506 ... P05326 11755401
    18006 1hb2:A (1.3) BS01 SCV 1.21.3.1 GO:0005506 ... P05326 11755401
    18007 1hb2:A (1.3) BS02 FE2 1.21.3.1 GO:0005506 ... P05326 11755401
    18008 1hb3:A (1.4) BS01 SCV 1.21.3.1 GO:0005506 ... P05326 11755401
    18009 1hb3:A (1.4) BS02 FE2 1.21.3.1 GO:0005506 ... P05326 11755401
    18010 1hb4:A (1.5) BS01 SCV 1.21.3.1 GO:0005506 ... P05326 11755401
    18011 1hb4:A (1.5) BS02 FE2 1.21.3.1 GO:0005506 ... P05326 11755401
    18012 1hba:A (2.1) BS01 HEM ? GO:0004601 ... P69905 1567857
    18013 1hba:B (2.1) BS01 HEM ? GO:0004601 ... P68871 1567857
    18014 1hba:C (2.1) BS01 HEM ? GO:0004601 ... P69905 1567857
    18015 1hba:D (2.1) BS01 HEM ? GO:0004601 ... P68871 1567857
    18016 1hbb:A (1.9) BS01 HEM ? GO:0004601 ... P69905 1567857
    18017 1hbb:B (1.9) BS01 HEM ? GO:0004601 ... P68871 1567857
    18018 1hbb:C (1.9) BS01 HEM ? GO:0004601 ... P69905 1567857
    18019 1hbb:D (1.9) BS01 HEM ? GO:0004601 ... P68871 1567857
    18020 1hbg:A (1.5) BS01 HEM ? GO:0001666 ... P02216 2585515
    18021 1hbh:A (2.2) BS01 HEM ? GO:0004601 ... P80043 7623382
    18022 1hbh:B (2.2) BS01 HEM ? GO:0004601 ... P80044 7623382
    18023 1hbh:C (2.2) BS01 HEM ? GO:0004601 ... P80043 7623382
    18024 1hbh:D (2.2) BS01 HEM ? GO:0004601 ... P80044 7623382
    18025 1hbi:A (1.7) BS01 HEM ? GO:0001666 ... P02213 7929217
    18026 1hbi:A (1.7) BS02 OXY ? GO:0001666 ... P02213 7929217
    18027 1hbi:A (1.7) BS03 HEM ? GO:0001666 ... P02213 7929217
    18028 1hbi:B (1.7) BS01 HEM ? GO:0001666 ... P02213 7929217
    18029 1hbi:B (1.7) BS02 HEM ? GO:0001666 ... P02213 7929217
    18030 1hbi:B (1.7) BS03 OXY ? GO:0001666 ... P02213 7929217
    18031 1hbj:A (2.5) BS01 FBQ 3.1.1.7 GO:0001507 ... P04058 11563919 PDBbind: -logKd/Ki=8.52, IC50=3.0nM
    BindingDB: IC50=11000nM
    18032 1hbk:A (2.0) BS01 COA ? GO:0000062 ... Q8IK57 11491287
    18033 1hbm:A (1.8) BS01 F43 2.8.4.1 GO:0005737 ... P11558 11491299
    18034 1hbm:A (1.8) BS02 SHT 2.8.4.1 GO:0005737 ... P11558 11491299
    18035 1hbm:A (1.8) BS03 F43 2.8.4.1 GO:0005737 ... P11558 11491299
    18036 1hbm:A (1.8) BS04 SHT 2.8.4.1 GO:0005737 ... P11558 11491299
    18037 1hbm:B (1.8) BS01 F43 2.8.4.1 GO:0005737 ... P11560 11491299
    18038 1hbm:B (1.8) BS02 SHT 2.8.4.1 GO:0005737 ... P11560 11491299
    18039 1hbm:C (1.8) BS01 F43 2.8.4.1 GO:0005737 ... P11562 11491299
    18040 1hbm:D (1.8) BS01 F43 2.8.4.1 GO:0005737 ... P11558 11491299
    18041 1hbm:D (1.8) BS02 SHT 2.8.4.1 GO:0005737 ... P11558 11491299
    18042 1hbm:D (1.8) BS03 F43 2.8.4.1 GO:0005737 ... P11558 11491299
    18043 1hbm:D (1.8) BS04 SHT 2.8.4.1 GO:0005737 ... P11558 11491299
    18044 1hbm:E (1.8) BS01 F43 2.8.4.1 GO:0005737 ... P11560 11491299
    18045 1hbm:E (1.8) BS02 SHT 2.8.4.1 GO:0005737 ... P11560 11491299
    18046 1hbm:F (1.8) BS01 F43 2.8.4.1 GO:0005737 ... P11562 11491299
    18047 1hbn:A (1.16) BS01 F43 2.8.4.1 GO:0005737 ... P11558 11491299
    18048 1hbn:A (1.16) BS02 TP7 2.8.4.1 GO:0005737 ... P11558 11491299
    18049 1hbn:A (1.16) BS03 COM 2.8.4.1 GO:0005737 ... P11558 11491299
    18050 1hbn:A (1.16) BS04 MG 2.8.4.1 GO:0005737 ... P11558 11491299
    18051 1hbn:A (1.16) BS05 F43 2.8.4.1 GO:0005737 ... P11558 11491299
    18052 1hbn:A (1.16) BS06 TP7 2.8.4.1 GO:0005737 ... P11558 11491299
    18053 1hbn:B (1.16) BS01 F43 2.8.4.1 GO:0005737 ... P11560 11491299
    18054 1hbn:B (1.16) BS02 TP7 2.8.4.1 GO:0005737 ... P11560 11491299
    18055 1hbn:B (1.16) BS03 COM 2.8.4.1 GO:0005737 ... P11560 11491299
    18056 1hbn:C (1.16) BS01 F43 2.8.4.1 GO:0005737 ... P11562 11491299
    18057 1hbn:D (1.16) BS01 F43 2.8.4.1 GO:0005737 ... P11558 11491299
    18058 1hbn:D (1.16) BS02 TP7 2.8.4.1 GO:0005737 ... P11558 11491299
    18059 1hbn:D (1.16) BS03 F43 2.8.4.1 GO:0005737 ... P11558 11491299
    18060 1hbn:D (1.16) BS04 TP7 2.8.4.1 GO:0005737 ... P11558 11491299
    18061 1hbn:D (1.16) BS05 COM 2.8.4.1 GO:0005737 ... P11558 11491299
    18062 1hbn:E (1.16) BS01 F43 2.8.4.1 GO:0005737 ... P11560 11491299
    18063 1hbn:E (1.16) BS02 TP7 2.8.4.1 GO:0005737 ... P11560 11491299
    18064 1hbn:E (1.16) BS03 COM 2.8.4.1 GO:0005737 ... P11560 11491299
    18065 1hbn:F (1.16) BS01 F43 2.8.4.1 GO:0005737 ... P11562 11491299
    18066 1hbn:F (1.16) BS02 MG 2.8.4.1 GO:0005737 ... P11562 11491299
    18067 1hbo:A (1.78) BS01 F43 2.8.4.1 GO:0005737 ... P11558 11491299
    18068 1hbo:A (1.78) BS02 TP7 2.8.4.1 GO:0005737 ... P11558 11491299
    18069 1hbo:A (1.78) BS03 COM 2.8.4.1 GO:0005737 ... P11558 11491299
    18070 1hbo:A (1.78) BS04 F43 2.8.4.1 GO:0005737 ... P11558 11491299
    18071 1hbo:A (1.78) BS05 TP7 2.8.4.1 GO:0005737 ... P11558 11491299
    18072 1hbo:B (1.78) BS01 F43 2.8.4.1 GO:0005737 ... P11560 11491299
    18073 1hbo:B (1.78) BS02 TP7 2.8.4.1 GO:0005737 ... P11560 11491299
    18074 1hbo:B (1.78) BS03 COM 2.8.4.1 GO:0005737 ... P11560 11491299
    18075 1hbo:C (1.78) BS01 F43 2.8.4.1 GO:0005737 ... P11562 11491299
    18076 1hbo:D (1.78) BS01 F43 2.8.4.1 GO:0005737 ... P11558 11491299
    18077 1hbo:D (1.78) BS02 TP7 2.8.4.1 GO:0005737 ... P11558 11491299
    18078 1hbo:D (1.78) BS03 F43 2.8.4.1 GO:0005737 ... P11558 11491299
    18079 1hbo:D (1.78) BS04 TP7 2.8.4.1 GO:0005737 ... P11558 11491299
    18080 1hbo:D (1.78) BS05 COM 2.8.4.1 GO:0005737 ... P11558 11491299
    18081 1hbo:E (1.78) BS01 F43 2.8.4.1 GO:0005737 ... P11560 11491299
    18082 1hbo:E (1.78) BS02 TP7 2.8.4.1 GO:0005737 ... P11560 11491299
    18083 1hbo:F (1.78) BS01 F43 2.8.4.1 GO:0005737 ... P11562 11491299
    18084 1hbp:A (1.9) BS01 RTL ? GO:0005501 ... P18902 8496140
    18085 1hbr:A (2.3) BS01 HEM ? GO:0004601 ... P02001 10037733
    18086 1hbr:B (2.3) BS01 HEM ? GO:0004601 ... P02112 10037733
    18087 1hbr:C (2.3) BS01 HEM ? GO:0004601 ... P02001 10037733
    18088 1hbr:D (2.3) BS01 HEM ? GO:0004601 ... P02112 10037733
    18089 1hbs:A (3.0) BS01 HEM ? GO:0004601 ... P69905 4008491
    18090 1hbs:B (3.0) BS01 HEM ? GO:0004601 ... P68871 4008491
    18091 1hbs:C (3.0) BS01 HEM ? GO:0004601 ... P69905 4008491
    18092 1hbs:D (3.0) BS01 HEM ? GO:0004601 ... P68871 4008491
    18093 1hbs:E (3.0) BS01 HEM ? GO:0004601 ... P69905 4008491
    18094 1hbs:F (3.0) BS01 HEM ? GO:0004601 ... P68871 4008491
    18095 1hbs:G (3.0) BS01 HEM ? GO:0004601 ... P69905 4008491
    18096 1hbs:H (3.0) BS01 HEM ? GO:0004601 ... P68871 4008491
    18097 1hbt:H (2.0) BS01 peptide 3.4.21.5 GO:0004252 ... P00734 7547884
    18098 1hbt:H (2.0) BS02 peptide 3.4.21.5 GO:0004252 ... P00734 7547884
    18099 1hbu:A (1.9) BS01 F43 2.8.4.1 GO:0005737 ... P11558 11491299
    18100 1hbu:A (1.9) BS02 TP7 2.8.4.1 GO:0005737 ... P11558 11491299
    18101 1hbu:A (1.9) BS03 COM 2.8.4.1 GO:0005737 ... P11558 11491299
    18102 1hbu:A (1.9) BS04 MG 2.8.4.1 GO:0005737 ... P11558 11491299
    18103 1hbu:A (1.9) BS05 F43 2.8.4.1 GO:0005737 ... P11558 11491299
    18104 1hbu:A (1.9) BS06 TP7 2.8.4.1 GO:0005737 ... P11558 11491299
    18105 1hbu:B (1.9) BS01 F43 2.8.4.1 GO:0005737 ... P11560 11491299
    18106 1hbu:B (1.9) BS02 TP7 2.8.4.1 GO:0005737 ... P11560 11491299
    18107 1hbu:B (1.9) BS03 COM 2.8.4.1 GO:0005737 ... P11560 11491299
    18108 1hbu:C (1.9) BS01 F43 2.8.4.1 GO:0005737 ... P11562 11491299
    18109 1hbu:D (1.9) BS01 F43 2.8.4.1 GO:0005737 ... P11558 11491299
    18110 1hbu:D (1.9) BS02 TP7 2.8.4.1 GO:0005737 ... P11558 11491299
    18111 1hbu:D (1.9) BS03 F43 2.8.4.1 GO:0005737 ... P11558 11491299
    18112 1hbu:D (1.9) BS04 TP7 2.8.4.1 GO:0005737 ... P11558 11491299
    18113 1hbu:D (1.9) BS05 COM 2.8.4.1 GO:0005737 ... P11558 11491299
    18114 1hbu:E (1.9) BS01 F43 2.8.4.1 GO:0005737 ... P11560 11491299
    18115 1hbu:E (1.9) BS02 TP7 2.8.4.1 GO:0005737 ... P11560 11491299
    18116 1hbu:E (1.9) BS03 COM 2.8.4.1 GO:0005737 ... P11560 11491299
    18117 1hbu:F (1.9) BS01 F43 2.8.4.1 GO:0005737 ... P11562 11491299
    18118 1hbv:A (2.3) BS01 GAN 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16
    GO:0004190 ... P03366 7650677 MOAD: Ki=430nM
    PDBbind: -logKd/Ki=6.37, Ki=430nM
    18119 1hbv:B (2.3) BS01 GAN 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16
    GO:0004190 ... P03366 7650677 PDBbind: -logKd/Ki=6.37, Ki=430nM
    18120 1hbx:A (3.15) BS01 dna ? GO:0000981 ... P11831 11406578
    18121 1hbx:A (3.15) BS02 dna ? GO:0000981 ... P11831 11406578
    18122 1hbx:B (3.15) BS01 dna ? GO:0000981 ... P11831 11406578
    18123 1hbx:B (3.15) BS02 dna ? GO:0000981 ... P11831 11406578
    18124 1hbx:D (3.15) BS01 dna ? GO:0000981 ... P11831 11406578
    18125 1hbx:D (3.15) BS02 dna ? GO:0000981 ... P11831 11406578
    18126 1hbx:E (3.15) BS01 dna ? GO:0000981 ... P11831 11406578
    18127 1hbx:E (3.15) BS02 dna ? GO:0000981 ... P11831 11406578
    18128 1hbx:G (3.15) BS01 dna ? GO:0003700 ... P28324 11406578
    18129 1hbx:G (3.15) BS02 dna ? GO:0003700 ... P28324 11406578
    18130 1hbx:H (3.15) BS01 dna ? GO:0003700 ... P28324 11406578
    18131 1hbx:H (3.15) BS02 dna ? GO:0003700 ... P28324 11406578
    18132 1hby:A (2.0) BS01 PO4 3.1.27.- GO:0001525 ... P03950 11468363
    18133 1hbz:A (1.5) BS01 HEM 1.11.1.6 GO:0004096 ... P29422 1426241
    18134 1hc1:A (3.2) BS01 CU ? GO:0005344 ... P04254 2585484
    18135 1hc1:A (3.2) BS02 CU ? GO:0005344 ... P04254 2585484
    18136 1hc1:B (3.2) BS01 CU ? GO:0005344 ... P04254 2585484
    18137 1hc1:B (3.2) BS02 CU ? GO:0005344 ... P04254 2585484
    18138 1hc1:C (3.2) BS01 CU ? GO:0005344 ... P04254 2585484
    18139 1hc1:C (3.2) BS02 CU ? GO:0005344 ... P04254 2585484
    18140 1hc1:D (3.2) BS01 CU ? GO:0005344 ... P04254 2585484
    18141 1hc1:D (3.2) BS02 CU ? GO:0005344 ... P04254 2585484
    18142 1hc1:E (3.2) BS01 CU ? GO:0005344 ... P04254 2585484
    18143 1hc1:E (3.2) BS02 CU ? GO:0005344 ... P04254 2585484
    18144 1hc1:F (3.2) BS01 CU ? GO:0005344 ... P04254 2585484
    18145 1hc1:F (3.2) BS02 CU ? GO:0005344 ... P04254 2585484
    18146 1hc7:A (2.43) BS01 ZN 6.1.1.15 GO:0000166 ... Q5SM28 11399074
    18147 1hc7:B (2.43) BS01 ZN 6.1.1.15 GO:0000166 ... Q5SM28 11399074
    18148 1hc7:C (2.43) BS01 ZN 6.1.1.15 GO:0000166 ... Q5SM28 11399074
    18149 1hc7:D (2.43) BS01 ZN 6.1.1.15 GO:0000166 ... Q5SM28 11399074
    18150 1hc8:A (2.8) BS01 rna ? GO:0003735 ... P56210 12054794
    18151 1hc8:B (2.8) BS01 rna ? GO:0003735 ... P56210 12054794
    18152 1hc9:A (1.8) BS01 peptide ? GO:0005515 ... P60616 11683996
    18153 1hc9:B (1.8) BS01 peptide ? GO:0005515 ... P60615 11683996
    18154 1hca:A (2.3) BS01 ZN 4.2.1.1
    4.2.1.69
    GO:0002009 ... P00918 N/A
    18155 1hcb:A (1.6) BS01 ZN 4.2.1.1
    4.2.1.69
    GO:0004064 ... P00915 8057362
    18156 1hcb:A (1.6) BS02 BCT 4.2.1.1
    4.2.1.69
    GO:0004064 ... P00915 8057362 BindingDB: Ki=12000000nM
    18157 1hch:A (1.57) BS01 HEM 1.11.1.7 GO:0004601 ... P00433 12024218
    18158 1hch:A (1.57) BS02 CA 1.11.1.7 GO:0004601 ... P00433 12024218
    18159 1hch:A (1.57) BS03 CA 1.11.1.7 GO:0004601 ... P00433 12024218
    18160 1hch:A (1.57) BS04 O 1.11.1.7 GO:0004601 ... P00433 12024218
    18161 1hck:A (1.9) BS01 MG 2.7.11.22 GO:0000082 ... P24941 8917641
    18162 1hck:A (1.9) BS02 ATP 2.7.11.22 GO:0000082 ... P24941 8917641
    18163 1hcm:A (2.5) BS01 HEC 1.7.2.1
    1.7.99.1
    GO:0009055 ... P72181 11373294
    18164 1hcm:A (2.5) BS02 DHE 1.7.2.1
    1.7.99.1
    GO:0009055 ... P72181 11373294
    18165 1hcm:B (2.5) BS01 HEC 1.7.2.1
    1.7.99.1
    GO:0009055 ... P72181 11373294
    18166 1hcm:B (2.5) BS02 DHE 1.7.2.1
    1.7.99.1
    GO:0009055 ... P72181 11373294
    18167 1hco:A (2.7) BS01 HEM ? GO:0004601 ... P69905 7373648
    18168 1hco:B (2.7) BS01 HEM ? GO:0004601 ... P68871 7373648
    18169 1hcp:A (-1.00) BS01 ZN ? GO:0003700 ... P03372 16100953
    18170 1hcp:A (-1.00) BS02 ZN ? GO:0003700 ... P03372 16100953
    18171 1hcq:A (2.4) BS01 dna ? GO:0003700 ... P03372 8221895
    18172 1hcq:A (2.4) BS02 dna ? GO:0003700 ... P03372 8221895
    18173 1hcq:A (2.4) BS03 ZN ? GO:0003700 ... P03372 8221895
    18174 1hcq:A (2.4) BS04 ZN ? GO:0003700 ... P03372 8221895
    18175 1hcq:B (2.4) BS01 dna ? GO:0003700 ... P03372 8221895
    18176 1hcq:B (2.4) BS02 dna ? GO:0003700 ... P03372 8221895
    18177 1hcq:B (2.4) BS03 ZN ? GO:0003700 ... P03372 8221895
    18178 1hcq:B (2.4) BS04 ZN ? GO:0003700 ... P03372 8221895
    18179 1hcq:E (2.4) BS01 dna ? GO:0003700 ... P03372 8221895
    18180 1hcq:E (2.4) BS02 dna ? GO:0003700 ... P03372 8221895
    18181 1hcq:E (2.4) BS03 ZN ? GO:0003700 ... P03372 8221895
    18182 1hcq:E (2.4) BS04 ZN ? GO:0003700 ... P03372 8221895
    18183 1hcq:F (2.4) BS01 dna ? GO:0003700 ... P03372 8221895
    18184 1hcq:F (2.4) BS02 dna ? GO:0003700 ... P03372 8221895
    18185 1hcq:F (2.4) BS03 ZN ? GO:0003700 ... P03372 8221895
    18186 1hcq:F (2.4) BS04 ZN ? GO:0003700 ... P03372 8221895
    18187 1hcr:A (2.3) BS01 dna ? GO:0000150 ... P03013 8278807
    18188 1hcr:A (2.3) BS02 dna ? GO:0000150 ... P03013 8278807
    18189 1hcs:B (-1.00) BS01 peptide 2.7.10.2 N/A P12931 7532003
    18190 1hct:B (-1.00) BS01 peptide 2.7.10.2 N/A P12931 7532003
    18191 1hcx:A (2.6) BS01 TPT 3.5.1.28 N/A P06653 11694890
    18192 1hcx:A (2.6) BS02 CHT 3.5.1.28 N/A P06653 11694890
    18193 1hcx:A (2.6) BS03 CHT 3.5.1.28 N/A P06653 11694890
    18194 1hcx:A (2.6) BS04 CHT 3.5.1.28 N/A P06653 11694890
    18195 1hcx:B (2.6) BS01 CHT 3.5.1.28 N/A P06653 11694890
    18196 1hcx:B (2.6) BS02 CHT 3.5.1.28 N/A P06653 11694890
    18197 1hcy:A (3.2) BS01 CU ? GO:0005344 ... P04254 2585484
    18198 1hcy:A (3.2) BS02 CU ? GO:0005344 ... P04254 2585484
    18199 1hcz:A (1.96) BS01 HEM ? GO:0005506 ... P36438 8762139
    18200 1hda:A (2.2) BS01 HEM ? GO:0004601 ... P01966 8411160

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218