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●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

BioLiP
Download all results in tab-seperated text for 594392 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    201001 5crg:D (1.97) BS10 CA ? GO:0005509 ... P31415 26416891
    201002 5crg:D (1.97) BS11 CA ? GO:0005509 ... P31415 26416891
    201003 5crg:D (1.97) BS12 CA ? GO:0005509 ... P31415 26416891
    201004 5crg:D (1.97) BS13 CA ? GO:0005509 ... P31415 26416891
    201005 5crg:D (1.97) BS14 CA ? GO:0005509 ... P31415 26416891
    201006 5crh:A (2.03) BS01 CA ? GO:0005509 ... P31415 26416891
    201007 5crh:A (2.03) BS02 CA ? GO:0005509 ... P31415 26416891
    201008 5crh:A (2.03) BS03 CA ? GO:0005509 ... P31415 26416891
    201009 5crh:A (2.03) BS04 CA ? GO:0005509 ... P31415 26416891
    201010 5crh:A (2.03) BS05 CA ? GO:0005509 ... P31415 26416891
    201011 5crh:A (2.03) BS06 CA ? GO:0005509 ... P31415 26416891
    201012 5crh:A (2.03) BS07 CA ? GO:0005509 ... P31415 26416891
    201013 5crh:A (2.03) BS08 CA ? GO:0005509 ... P31415 26416891
    201014 5crh:B (2.03) BS01 CA ? GO:0005509 ... P31415 26416891
    201015 5crh:B (2.03) BS02 CA ? GO:0005509 ... P31415 26416891
    201016 5crh:B (2.03) BS03 CA ? GO:0005509 ... P31415 26416891
    201017 5crh:B (2.03) BS04 CA ? GO:0005509 ... P31415 26416891
    201018 5crh:B (2.03) BS05 CA ? GO:0005509 ... P31415 26416891
    201019 5crh:B (2.03) BS06 CA ? GO:0005509 ... P31415 26416891
    201020 5crh:B (2.03) BS07 CA ? GO:0005509 ... P31415 26416891
    201021 5crh:B (2.03) BS08 CA ? GO:0005509 ... P31415 26416891
    201022 5cry:A (2.79) BS01 FE 3.4.21.- GO:0005576 ... P24627 N/A
    201023 5cry:A (2.79) BS02 BCT 3.4.21.- GO:0005576 ... P24627 N/A
    201024 5cry:B (2.79) BS01 FE 3.4.21.- GO:0005576 ... P24627 N/A
    201025 5cry:B (2.79) BS02 BCT 3.4.21.- GO:0005576 ... P24627 N/A
    201026 5csf:A (2.4) BS01 peptide ? GO:0001726 ... P04271 26527685
    201027 5csf:A (2.4) BS02 CA ? GO:0001726 ... P04271 26527685
    201028 5csf:A (2.4) BS03 CA ? GO:0001726 ... P04271 26527685
    201029 5csf:B (2.4) BS01 peptide ? GO:0001726 ... P04271 26527685
    201030 5csf:B (2.4) BS02 CA ? GO:0001726 ... P04271 26527685
    201031 5csf:B (2.4) BS03 CA ? GO:0001726 ... P04271 26527685
    201032 5csi:A (2.13) BS01 peptide ? GO:0001726 ... P04271 26527685
    201033 5csi:A (2.13) BS02 CA ? GO:0001726 ... P04271 26527685
    201034 5csi:A (2.13) BS03 CA ? GO:0001726 ... P04271 26527685
    201035 5csi:B (2.13) BS01 peptide ? GO:0001726 ... P04271 26527685
    201036 5csi:B (2.13) BS02 CA ? GO:0001726 ... P04271 26527685
    201037 5csi:B (2.13) BS03 CA ? GO:0001726 ... P04271 26527685
    201038 5csj:A (2.7) BS01 peptide ? GO:0001726 ... P04271 26527685
    201039 5csj:A (2.7) BS02 CA ? GO:0001726 ... P04271 26527685
    201040 5csj:A (2.7) BS03 CA ? GO:0001726 ... P04271 26527685
    201041 5csj:B (2.7) BS01 peptide ? GO:0001726 ... P04271 26527685
    201042 5csj:B (2.7) BS02 CA ? GO:0001726 ... P04271 26527685
    201043 5csj:B (2.7) BS03 CA ? GO:0001726 ... P04271 26527685
    201044 5csl:A (3.2) BS01 BTI 6.3.4.14
    6.4.1.2    		 GO:0003989 ... Q00955 26458104
    201045 5csl:A (3.2) BS02 COA 6.3.4.14
    6.4.1.2    		 GO:0003989 ... Q00955 26458104
    201046 5csl:B (3.2) BS01 BTI 6.3.4.14
    6.4.1.2    		 GO:0003989 ... Q00955 26458104
    201047 5csl:B (3.2) BS02 COA 6.3.4.14
    6.4.1.2    		 GO:0003989 ... Q00955 26458104
    201048 5csm:A (2.0) BS01 TRP 5.4.99.5 GO:0004106 ... P32178 9384560
    201049 5csn:A (2.95) BS01 peptide ? GO:0001726 ... P04271 26527685
    201050 5csn:A (2.95) BS02 CA ? GO:0001726 ... P04271 26527685
    201051 5csn:A (2.95) BS03 CA ? GO:0001726 ... P04271 26527685
    201052 5csn:B (2.95) BS01 peptide ? GO:0001726 ... P04271 26527685
    201053 5csn:B (2.95) BS02 CA ? GO:0001726 ... P04271 26527685
    201054 5csn:B (2.95) BS03 CA ? GO:0001726 ... P04271 26527685
    201055 5csr:A (1.94) BS01 GOL 5.3.1.1 GO:0004807 ... Q9HLB6 26709515
    201056 5csr:B (1.94) BS01 GOL 5.3.1.1 GO:0004807 ... Q9HLB6 26709515
    201057 5csr:C (1.94) BS01 GOL 5.3.1.1 GO:0004807 ... Q9HLB6 26709515
    201058 5csr:D (1.94) BS01 GOL 5.3.1.1 GO:0004807 ... Q9HLB6 26709515
    201059 5css:A (2.17) BS01 G3P 5.3.1.1 GO:0004807 ... Q9HLB6 26709515
    201060 5css:B (2.17) BS01 G3P 5.3.1.1 GO:0004807 ... Q9HLB6 26709515
    201061 5css:C (2.17) BS01 G3P 5.3.1.1 GO:0004807 ... Q9HLB6 26709515
    201062 5css:D (2.17) BS01 G3P 5.3.1.1 GO:0004807 ... Q9HLB6 26709515
    201063 5csu:A (2.53) BS01 GLC 2.4.1.25 GO:0000025 ... Q9LV91 26504082
    201064 5csu:A (2.53) BS02 AGL 2.4.1.25 GO:0000025 ... Q9LV91 26504082
    201065 5csu:A (2.53) BS03 BGC 2.4.1.25 GO:0000025 ... Q9LV91 26504082
    201066 5csu:A (2.53) BS04 GLC 2.4.1.25 GO:0000025 ... Q9LV91 26504082
    201067 5csu:A (2.53) BS05 AGL 2.4.1.25 GO:0000025 ... Q9LV91 26504082
    201068 5csu:A (2.53) BS06 HMC 2.4.1.25 GO:0000025 ... Q9LV91 26504082
    201069 5csu:B (2.53) BS01 GLC 2.4.1.25 GO:0000025 ... Q9LV91 26504082
    201070 5csu:B (2.53) BS02 AGL 2.4.1.25 GO:0000025 ... Q9LV91 26504082
    201071 5csu:B (2.53) BS03 BGC 2.4.1.25 GO:0000025 ... Q9LV91 26504082
    201072 5csu:B (2.53) BS04 GLC 2.4.1.25 GO:0000025 ... Q9LV91 26504082
    201073 5csu:B (2.53) BS05 AGL 2.4.1.25 GO:0000025 ... Q9LV91 26504082
    201074 5csu:B (2.53) BS06 HMC 2.4.1.25 GO:0000025 ... Q9LV91 26504082
    201075 5csy:A (2.05) BS01 BGC 2.4.1.25 GO:0000025 ... Q9LV91 26504082
    201076 5csy:A (2.05) BS02 GLC 2.4.1.25 GO:0000025 ... Q9LV91 26504082
    201077 5csy:A (2.05) BS03 GLC 2.4.1.25 GO:0000025 ... Q9LV91 26504082
    201078 5csy:A (2.05) BS04 BGC 2.4.1.25 GO:0000025 ... Q9LV91 26504082
    201079 5csy:A (2.05) BS05 GLC 2.4.1.25 GO:0000025 ... Q9LV91 26504082
    201080 5csy:B (2.05) BS01 GLC 2.4.1.25 GO:0000025 ... Q9LV91 26504082
    201081 5csy:B (2.05) BS02 GLC 2.4.1.25 GO:0000025 ... Q9LV91 26504082
    201082 5csy:B (2.05) BS03 AC1 2.4.1.25 GO:0000025 ... Q9LV91 26504082
    201083 5csy:B (2.05) BS04 GLC 2.4.1.25 GO:0000025 ... Q9LV91 26504082
    201084 5csy:B (2.05) BS05 GLC 2.4.1.25 GO:0000025 ... Q9LV91 26504082
    201085 5ct4:A (1.49) BS01 BM0 3.1.1.3 GO:0004806 ... P37957 26388426
    201086 5ct4:A (1.49) BS02 CL 3.1.1.3 GO:0004806 ... P37957 26388426
    201087 5ct5:A (1.747) BS01 CL 3.1.1.3 GO:0004806 ... P37957 26388426
    201088 5ct6:A (1.902) BS01 CL 3.1.1.3 GO:0004806 ... P37957 26388426
    201089 5ct6:A (1.902) BS02 BM0 3.1.1.3 GO:0004806 ... P37957 26388426
    201090 5ct6:A (1.902) BS03 BM0 3.1.1.3 GO:0004806 ... P37957 26388426
    201091 5ct6:A (1.902) BS04 BM0 3.1.1.3 GO:0004806 ... P37957 26388426
    201092 5ct6:A (1.902) BS05 BM0 3.1.1.3 GO:0004806 ... P37957 26388426
    201093 5ct6:B (1.902) BS01 BM0 3.1.1.3 GO:0004806 ... P37957 26388426
    201094 5ct6:B (1.902) BS02 CL 3.1.1.3 GO:0004806 ... P37957 26388426
    201095 5ct6:B (1.902) BS03 BM0 3.1.1.3 GO:0004806 ... P37957 26388426
    201096 5ct6:B (1.902) BS04 BM0 3.1.1.3 GO:0004806 ... P37957 26388426
    201097 5ct9:A (1.4) BS01 CL 3.1.1.3 GO:0004806 ... P37957 26388426
    201098 5ct9:A (1.4) BS02 BM0 3.1.1.3 GO:0004806 ... P37957 26388426
    201099 5cta:A (1.24) BS01 BM0 3.1.1.3 GO:0004806 ... P37957 26388426
    201100 5cta:A (1.24) BS02 CL 3.1.1.3 GO:0004806 ... P37957 26388426
    201101 5cts:A (1.9) BS01 OAA 2.3.3.1 GO:0004108 ... P23007 2337600
    201102 5cts:A (1.9) BS02 CMC 2.3.3.1 GO:0004108 ... P23007 2337600
    201103 5ctt:A (1.7) BS01 peptide ? GO:0005737 ... P52293 27060135
    201104 5cu1:A (2.3) BS01 FE 4.4.1.3 GO:0003674 ... Q5LT18 N/A
    201105 5cuh:A (1.83) BS01 ZN 3.4.24.35 GO:0004222 ... P14780 26871660
    201106 5cuh:A (1.83) BS02 ZN 3.4.24.35 GO:0004222 ... P14780 26871660
    201107 5cuh:A (1.83) BS03 CA 3.4.24.35 GO:0004222 ... P14780 26871660
    201108 5cuh:A (1.83) BS04 CA 3.4.24.35 GO:0004222 ... P14780 26871660
    201109 5cuh:A (1.83) BS05 CA 3.4.24.35 GO:0004222 ... P14780 26871660
    201110 5cuh:A (1.83) BS06 LTQ 3.4.24.35 GO:0004222 ... P14780 26871660 PDBbind: -logKd/Ki=4.62, IC50=24uM
    BindingDB: IC50=24000nM
    201111 5cuh:B (1.83) BS01 ZN 3.4.24.35 GO:0004222 ... P14780 26871660
    201112 5cuh:B (1.83) BS02 ZN 3.4.24.35 GO:0004222 ... P14780 26871660
    201113 5cuh:B (1.83) BS03 CA 3.4.24.35 GO:0004222 ... P14780 26871660
    201114 5cuh:B (1.83) BS04 CA 3.4.24.35 GO:0004222 ... P14780 26871660
    201115 5cuh:B (1.83) BS05 CA 3.4.24.35 GO:0004222 ... P14780 26871660
    201116 5cuh:B (1.83) BS06 LTQ 3.4.24.35 GO:0004222 ... P14780 26871660 BindingDB: IC50=24000nM
    201117 5cuj:A (2.08) BS01 CA ? GO:0005576 ... Q01523 29858013
    201118 5cuj:B (2.08) BS01 CA ? GO:0005576 ... Q01523 29858013
    201119 5cuj:C (2.08) BS01 CA ? GO:0005576 ... Q01523 29858013
    201120 5cuj:D (2.08) BS01 CA ? GO:0005576 ... Q01523 29858013
    201121 5cuj:E (2.08) BS01 CA ? GO:0005576 ... Q01523 29858013
    201122 5cuj:F (2.08) BS01 CA ? GO:0005576 ... Q01523 29858013
    201123 5cul:B (2.9) BS01 peptide ? GO:0009306 ... Q9I337 26589798
    201124 5cum:A (1.752) BS01 CA ? GO:0005576 ... Q01523 29858013
    201125 5cum:B (1.752) BS01 CA ? GO:0005576 ... Q01523 29858013
    201126 5cum:C (1.752) BS01 CA ? GO:0005576 ... Q01523 29858013
    201127 5cur:A (1.302) BS01 BM0 3.1.1.3 GO:0004806 ... P37957 26388426
    201128 5cur:A (1.302) BS02 BM0 3.1.1.3 GO:0004806 ... P37957 26388426
    201129 5cur:A (1.302) BS03 BM0 3.1.1.3 GO:0004806 ... P37957 26388426
    201130 5cur:A (1.302) BS04 BM0 3.1.1.3 GO:0004806 ... P37957 26388426
    201131 5cur:A (1.302) BS05 CL 3.1.1.3 GO:0004806 ... P37957 26388426
    201132 5cur:A (1.302) BS06 CL 3.1.1.3 GO:0004806 ... P37957 26388426
    201133 5cuu:A (2.96) BS01 4GA 3.6.1.1 GO:0000287 ... Q4JH30 N/A PDBbind: -logKd/Ki=4.37, IC50=42.3uM
    201134 5cuu:B (2.96) BS01 4GA 3.6.1.1 GO:0000287 ... Q4JH30 N/A
    201135 5cuv:A (2.62) BS01 MG 3.6.1.1 GO:0000287 ... Q4JH30 N/A
    201136 5cuv:B (2.62) BS01 MG 3.6.1.1 GO:0000287 ... Q4JH30 N/A
    201137 5cux:A (2.8) BS01 POP 3.6.1.1 GO:0000287 ... Q4JH30 N/A
    201138 5cux:A (2.8) BS02 POP 3.6.1.1 GO:0000287 ... Q4JH30 N/A
    201139 5cux:B (2.8) BS01 POP 3.6.1.1 GO:0000287 ... Q4JH30 N/A
    201140 5cuy:A (2.5) BS01 MG 3.6.1.1 GO:0000287 ... Q384W3 N/A
    201141 5cuy:B (2.5) BS01 MG 3.6.1.1 GO:0000287 ... Q384W3 N/A
    201142 5cuy:C (2.5) BS01 MG 3.6.1.1 GO:0000287 ... Q384W3 N/A
    201143 5cuy:D (2.5) BS01 MG 3.6.1.1 GO:0000287 ... Q384W3 N/A
    201144 5cvd:A (1.3) BS01 peptide 2.1.1.244 GO:0005515 ... Q9BV86 26543159
    201145 5cvd:A (1.3) BS02 SAH 2.1.1.244 GO:0005515 ... Q9BV86 26543159
    201146 5cvd:B (1.3) BS01 peptide 2.1.1.244 GO:0005515 ... Q9BV86 26543159
    201147 5cvd:B (1.3) BS02 SAH 2.1.1.244 GO:0005515 ... Q9BV86 26543159
    201148 5cve:A (1.5) BS01 peptide 2.1.1.244 GO:0005515 ... Q9BV86 26543159
    201149 5cve:A (1.5) BS02 SAH 2.1.1.244 GO:0005515 ... Q9BV86 26543159
    201150 5cve:B (1.5) BS01 peptide 2.1.1.244 GO:0005515 ... Q9BV86 26543159
    201151 5cve:B (1.5) BS02 SAH 2.1.1.244 GO:0005515 ... Q9BV86 26543159
    201152 5cvm:A (1.9) BS01 ZN 3.4.19.12 GO:0001662 ... P62068 26388029
    201153 5cvn:B (3.36) BS01 ZN 3.4.19.12 GO:0001662 ... P62068 26388029
    201154 5cvo:B (3.885) BS01 ZN 3.4.19.12 GO:0001662 ... P62068 26388029
    201155 5cvo:E (3.885) BS01 ZN 3.4.19.12 GO:0001662 ... P62068 26388029
    201156 5cvr:A (2.6) BS01 FES ? GO:0003677 ... Q70ET4 26665177
    201157 5cw3:A (2.55) BS01 ZN 3.4.19.- GO:0000922 ... E2AXC7 26344097
    201158 5cw3:C (2.55) BS01 ZN 3.4.19.- GO:0000922 ... E2AXC7 26344097
    201159 5cw4:A (2.543) BS01 ZN 3.4.19.- GO:0000922 ... E2AXC7 26344097
    201160 5cw6:A (3.193) BS01 ZN 3.4.19.- GO:0000922 ... A0A8M3B525 26344097
    201161 5cx1:A (1.7476) BS01 ICS 1.18.6.1 GO:0005524 ... P07328 26360912
    201162 5cx1:A (1.7476) BS02 CLF 1.18.6.1 GO:0005524 ... P07328 26360912
    201163 5cx1:B (1.7476) BS01 CLF 1.18.6.1 GO:0005524 ... P07329 26360912
    201164 5cx1:B (1.7476) BS02 CA 1.18.6.1 GO:0005524 ... P07329 26360912
    201165 5cx1:B (1.7476) BS03 CA 1.18.6.1 GO:0005524 ... P07329 26360912
    201166 5cx1:C (1.7476) BS01 ICS 1.18.6.1 GO:0005524 ... P07328 26360912
    201167 5cx1:C (1.7476) BS02 CLF 1.18.6.1 GO:0005524 ... P07328 26360912
    201168 5cx1:D (1.7476) BS01 CA 1.18.6.1 GO:0005524 ... P07329 26360912
    201169 5cx1:D (1.7476) BS02 CLF 1.18.6.1 GO:0005524 ... P07329 26360912
    201170 5cx1:D (1.7476) BS03 CA 1.18.6.1 GO:0005524 ... P07329 26360912
    201171 5cx1:E (1.7476) BS01 ICS 1.18.6.1 GO:0005524 ... P07328 26360912
    201172 5cx1:E (1.7476) BS02 CLF 1.18.6.1 GO:0005524 ... P07328 26360912
    201173 5cx1:F (1.7476) BS01 CLF 1.18.6.1 GO:0005524 ... P07329 26360912
    201174 5cx1:F (1.7476) BS02 CA 1.18.6.1 GO:0005524 ... P07329 26360912
    201175 5cx1:F (1.7476) BS03 CA 1.18.6.1 GO:0005524 ... P07329 26360912
    201176 5cx1:G (1.7476) BS01 ICS 1.18.6.1 GO:0005524 ... P07328 26360912
    201177 5cx1:G (1.7476) BS02 CLF 1.18.6.1 GO:0005524 ... P07328 26360912
    201178 5cx1:H (1.7476) BS01 CA 1.18.6.1 GO:0005524 ... P07329 26360912
    201179 5cx1:H (1.7476) BS02 CLF 1.18.6.1 GO:0005524 ... P07329 26360912
    201180 5cx1:H (1.7476) BS03 CA 1.18.6.1 GO:0005524 ... P07329 26360912
    201181 5cx1:I (1.7476) BS01 ICS 1.18.6.1 GO:0005524 ... P07328 26360912
    201182 5cx1:I (1.7476) BS02 CLF 1.18.6.1 GO:0005524 ... P07328 26360912
    201183 5cx1:J (1.7476) BS01 CLF 1.18.6.1 GO:0005524 ... P07329 26360912
    201184 5cx1:J (1.7476) BS02 CA 1.18.6.1 GO:0005524 ... P07329 26360912
    201185 5cx1:J (1.7476) BS03 CA 1.18.6.1 GO:0005524 ... P07329 26360912
    201186 5cx1:K (1.7476) BS01 ICS 1.18.6.1 GO:0005524 ... P07328 26360912
    201187 5cx1:K (1.7476) BS02 CLF 1.18.6.1 GO:0005524 ... P07328 26360912
    201188 5cx1:L (1.7476) BS01 CA 1.18.6.1 GO:0005524 ... P07329 26360912
    201189 5cx1:L (1.7476) BS02 CLF 1.18.6.1 GO:0005524 ... P07329 26360912
    201190 5cx1:L (1.7476) BS03 CA 1.18.6.1 GO:0005524 ... P07329 26360912
    201191 5cx1:M (1.7476) BS01 ICS 1.18.6.1 GO:0005524 ... P07328 26360912
    201192 5cx1:M (1.7476) BS02 CLF 1.18.6.1 GO:0005524 ... P07328 26360912
    201193 5cx1:N (1.7476) BS01 CLF 1.18.6.1 GO:0005524 ... P07329 26360912
    201194 5cx1:N (1.7476) BS02 CA 1.18.6.1 GO:0005524 ... P07329 26360912
    201195 5cx1:N (1.7476) BS03 CA 1.18.6.1 GO:0005524 ... P07329 26360912
    201196 5cx1:O (1.7476) BS01 ICS 1.18.6.1 GO:0005524 ... P07328 26360912
    201197 5cx1:O (1.7476) BS02 CLF 1.18.6.1 GO:0005524 ... P07328 26360912
    201198 5cx1:P (1.7476) BS01 CA 1.18.6.1 GO:0005524 ... P07329 26360912
    201199 5cx1:P (1.7476) BS02 CLF 1.18.6.1 GO:0005524 ... P07329 26360912
    201200 5cx1:P (1.7476) BS03 CA 1.18.6.1 GO:0005524 ... P07329 26360912
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023)(download the PDF file).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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