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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	865231-46-5
Molecular formula	C26H21F3O3
IUPAC name	(3S)-3-[4-[[3-[4-(trifluoromethyl)phenyl]phenyl]methoxy]phenyl]hex-4-ynoic acid
Molecular weight	438.446
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	6.2
Synonyms	(3S)-3-[4-({3-[4-(trifluoromethyl)phenyl]phenyl}methoxy)phenyl]hex-4-ynoic acid AJ-119043 B5834 DTXSID00676764 SB16974 3568AC AMG-837 C26H21F3O3 GTPL6485 ZINC72118116 AS-51920 CS-3278 NCGC00386948-01 (S)-3-(4-((4'-(Trifluoromethyl)-[1,1'-biphenyl]-3-yl)methoxy)phenyl)hex-4-ynoic acid AKOS016009081 BC600585 EX-A1792 SCHEMBL12194429 AMG837 HY-13967 (3S)-3-(4-{[4'-(Trifluoromethyl)[1,1'-biphenyl]-3-yl]methoxy}phenyl)hex-4-ynoic acid AC-30223 AX8228266 D0Q7BG NE6U6R66U4 (S)-3-[4-[4'-(Trifluoromethyl)-3-biphenylylmethoxy]phenyl]-4-hexynoic acid AMG 837 BDBM50362690 FT-0772001 UNII-NE6U6R66U4 API0019508 CHEMBL1829173 KB-211342 [ Show all ]
Inchi Key	ZOPNBMMVVZRSGH-NRFANRHFSA-N
Inchi ID	InChI=1S/C26H21F3O3/c1-2-4-21(16-25(30)31)20-9-13-24(14-10-20)32-17-18-5-3-6-22(15-18)19-7-11-23(12-8-19)26(27,28)29/h3,5-15,21H,16-17H2,1H3,(H,30,31)/t21-/m0/s1
PubChem CID	46854655
ChEMBL	CHEMBL1829173
IUPHAR	6485
BindingDB	50362690
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
433633	Free fatty acid receptor 1	O14842	FFAR1	Homo sapiens (Human)	300
433634	Free fatty acid receptor 1	Q76JU9	Ffar1	Mus musculus (Mouse)	300
433635	Free fatty acid receptor 1	Q8K3T4	Ffar1	Rattus norvegicus (Rat)	300

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