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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL221664
Molecular formula	C26H31FN2O3
IUPAC name	2-[2-[4-(1-butyl-6-fluoroindol-3-yl)piperidin-1-yl]ethoxy]benzoic acid
Molecular weight	438.543
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	2.8
Synonyms	BDBM50156879 2-{2-[4-(1-butyl-6-fluoro-1H-indol-3-yl)piperidin-1-yl]-ethoxy}benzoic acid
Inchi Key	ZMOAWDWBPDLQAJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H31FN2O3/c1-2-3-12-29-18-23(21-9-8-20(27)17-24(21)29)19-10-13-28(14-11-19)15-16-32-25-7-5-4-6-22(25)26(30)31/h4-9,17-19H,2-3,10-16H2,1H3,(H,30,31)
PubChem CID	11189839
ChEMBL	CHEMBL221664
IUPHAR	N/A
BindingDB	50156879
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
432240	Histamine H1 receptor	P70174	Hrh1	Mus musculus (Mouse)	488
432241	Histamine H1 receptor	P31389	HRH1	Cavia porcellus (Guinea pig)	488
432239	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359

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