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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL221716
Molecular formula	C27H34N2O5
IUPAC name	2-[2-[4-[1-(2-ethoxyethyl)-5-methoxyindol-3-yl]piperidin-1-yl]ethoxy]benzoic acid
Molecular weight	466.578
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	1.6
Synonyms	BDBM50156883 SCHEMBL6780286 2-(2-{4-[1-(2-ethoxyethyl)-5-methoxy-1H-indol-3-yl]piperidin-1-yl}ethoxy)benzoic acid
Inchi Key	ZEARTZKNFQZDKX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H34N2O5/c1-3-33-16-15-29-19-24(23-18-21(32-2)8-9-25(23)29)20-10-12-28(13-11-20)14-17-34-26-7-5-4-6-22(26)27(30)31/h4-9,18-20H,3,10-17H2,1-2H3,(H,30,31)
PubChem CID	11351801
ChEMBL	CHEMBL221716
IUPHAR	N/A
BindingDB	50156883
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
426101	Histamine H1 receptor	P31389	HRH1	Cavia porcellus (Guinea pig)	488
426102	Histamine H1 receptor	P70174	Hrh1	Mus musculus (Mouse)	488
426103	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359

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