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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Ap4A
Molecular formula	C20H24N10O19P4-4
IUPAC name	[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] [[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] phosphate
Molecular weight	832.358
Hydrogen bond acceptor	27
Hydrogen bond donor	6
XlogP	-8.6
Synonyms	ADENOSYL-P4 P(1),P(4)-bis(5'-adenosyl) tetraphosphate tetraanion CHEBI:58141 P1,P4-Bis(5'-adenosyl) tetraphosphate F-1500 (tetraNa salt) P(1),P(4)-bis(5'-adenosyl) tetraphosphate(4-) D0UF2N [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphonato}oxy)phosphinato]oxy}phosphinato)oxy]phosphonate 3loo GTPL1732 bis(5'-adenosyl) tetraphosphate P(1),P(4)-bis(5'-adenosyl)tetraphosphate Diadenosine 5',5''-P1,P4-tetraphosphate [ Show all ]
Inchi Key	YOAHKNVSNCMZGQ-XPWFQUROSA-J
Inchi ID	InChI=1S/C20H28N10O19P4/c21-15-9-17(25-3-23-15)29(5-27-9)19-13(33)11(31)7(45-19)1-43-50(35,36)47-52(39,40)49-53(41,42)48-51(37,38)44-2-8-12(32)14(34)20(46-8)30-6-28-10-16(22)24-4-26-18(10)30/h3-8,11-14,19-20,31-34H,1-2H2,(H,35,36)(H,37,38)(H,39,40)(H,41,42)(H2,21,23,25)(H2,22,24,26)/p-4/t7-,8-,11-,12-,13-,14-,19-,20-/m1/s1
PubChem CID	25243905
ChEMBL	N/A
IUPHAR	1732
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
555351	P2Y purinoceptor 12	Q9H244	P2RY12	Homo sapiens (Human)	342
555350	P2Y purinoceptor 13	Q9BPV8	P2RY13	Homo sapiens (Human)	354
555352	P2Y purinoceptor 2	P41231	P2RY2	Homo sapiens (Human)	377
555353	P2Y purinoceptor 4	O35811	P2ry4	Rattus norvegicus (Rat)	361

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