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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL295563
Molecular formula	C22H30N4O2
IUPAC name	3-(2,4-dimethoxyphenyl)-2,5-dimethyl-N,N-dipropylpyrazolo[1,5-a]pyrimidin-7-amine
Molecular weight	382.508
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	4.9
Synonyms	[3-(2,4-Dimethoxy-phenyl)-2,5-dimethyl-pyrazolo[1,5-a]pyrimidin-7-yl]-dipropyl-amine BDBM50087707 N,N-Dipropyl-2,5-dimethyl-3-(2,4-dimethoxyphenyl)pyrazolo[1,5-a]pyrimidine-7-amine [3-(2,4-Dimethoxy-phenyl)-2,5-dimethyl-3H-pyrazolo[1,5-a]pyrimidin-7-yl]-dipropyl-amine
Inchi Key	YGIHMRSIPWHSFR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H30N4O2/c1-7-11-25(12-8-2)20-13-15(3)23-22-21(16(4)24-26(20)22)18-10-9-17(27-5)14-19(18)28-6/h9-10,13-14H,7-8,11-12H2,1-6H3
PubChem CID	44290322
ChEMBL	CHEMBL295563
IUPHAR	N/A
BindingDB	50087707
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
409488	Corticotropin-releasing factor receptor 1	P34998	CRHR1	Homo sapiens (Human)	444
409487	Corticotropin-releasing factor receptor 2	Q13324	CRHR2	Homo sapiens (Human)	411

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