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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3401383
Molecular formula	C31H36FN3O5
IUPAC name	N-[3-(4-carbamoylphenoxy)-5-(4-fluorophenoxy)phenyl]-4-(2-ethylbutyl)-4-hydroxypiperidine-1-carboxamide
Molecular weight	549.643
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	5.6
Synonyms	BDBM50065611 SCHEMBL14839322
Inchi Key	XWGOCGLJLLJAOE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C31H36FN3O5/c1-3-21(4-2)20-31(38)13-15-35(16-14-31)30(37)34-24-17-27(39-25-9-5-22(6-10-25)29(33)36)19-28(18-24)40-26-11-7-23(32)8-12-26/h5-12,17-19,21,38H,3-4,13-16,20H2,1-2H3,(H2,33,36)(H,34,37)
PubChem CID	89484779
ChEMBL	CHEMBL3401383
IUPHAR	N/A
BindingDB	50065611
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
457662	Lysophosphatidic acid receptor 1	Q92633	LPAR1	Homo sapiens (Human)	364
457663	Lysophosphatidic acid receptor 2	Q9HBW0	LPAR2	Homo sapiens (Human)	351
457664	Sphingosine 1-phosphate receptor 2	O95136	S1PR2	Homo sapiens (Human)	353
512550	Sphingosine 1-phosphate receptor 2	P47752	S1pr2	Rattus norvegicus (Rat)	352
457665	Sphingosine 1-phosphate receptor 3	Q99500	S1PR3	Homo sapiens (Human)	378

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