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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3897835
Molecular formula	C22H25ClN2O3
IUPAC name	2-[(2S)-2-[(3-chlorophenoxy)methyl]morpholin-4-yl]-1-(2-methyl-2,3-dihydroindol-1-yl)ethanone
Molecular weight	400.903
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	3.8
Synonyms	US9079895, 64 BDBM186962 SCHEMBL15746096
Inchi Key	XRYWJXIFEBMFIK-FZCLLLDFSA-N
Inchi ID	InChI=1S/C22H25ClN2O3/c1-16-11-17-5-2-3-8-21(17)25(16)22(26)14-24-9-10-27-20(13-24)15-28-19-7-4-6-18(23)12-19/h2-8,12,16,20H,9-11,13-15H2,1H3/t16?,20-/m0/s1
PubChem CID	71618702
ChEMBL	CHEMBL3897835
IUPHAR	N/A
BindingDB	186962
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
546739	5-hydroxytryptamine receptor 1A	Q64264	Htr1a	Mus musculus (Mouse)	421
546741	5-hydroxytryptamine receptor 2A	P35363	Htr2a	Mus musculus (Mouse)	471
546738	5-hydroxytryptamine receptor 2B	Q02152	Htr2b	Mus musculus (Mouse)	479
546740	Alpha-1D adrenergic receptor	P97714	Adra1d	Mus musculus (Mouse)	562
546742	D(4) dopamine receptor	P51436	Drd4	Mus musculus (Mouse)	387

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