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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2349335
Molecular formula	C18H23N5OS2
IUPAC name	(2R)-2-[(2-amino-5-benzylsulfanyl-[1,3]thiazolo[4,5-d]pyrimidin-7-yl)amino]-4-methylpentan-1-ol
Molecular weight	389.536
Hydrogen bond acceptor	8
Hydrogen bond donor	3
XlogP	4.4
Synonyms	XCVNKDBFHMYYDO-CYBMUJFWSA-N BDBM50432446 SCHEMBL5233299 (R)-2-(2-amino-5-phenylmethylthio-thiazolo[4,5-d]pyrimidin-7-ylamino)-4-methyl-pentan-1-ol
Inchi Key	XCVNKDBFHMYYDO-CYBMUJFWSA-N
Inchi ID	InChI=1S/C18H23N5OS2/c1-11(2)8-13(9-24)20-15-14-16(21-17(19)26-14)23-18(22-15)25-10-12-6-4-3-5-7-12/h3-7,11,13,24H,8-10H2,1-2H3,(H3,19,20,21,22,23)/t13-/m1/s1
PubChem CID	58230405
ChEMBL	CHEMBL2349335
IUPHAR	N/A
BindingDB	50432446
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
388679	C-X-C chemokine receptor type 2	P25025	CXCR2	Homo sapiens (Human)	360
388678	CX3C chemokine receptor 1	P49238	CX3CR1	Homo sapiens (Human)	355

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