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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL450471
Molecular formula	C30H26ClF4N3O4
IUPAC name	4-[[(1R)-2-[5-(2-chlorophenyl)-3-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-2,6-dioxopyrimidin-1-yl]-1-phenylethyl]amino]butanoic acid
Molecular weight	603.999
Hydrogen bond acceptor	9
Hydrogen bond donor	2
XlogP	2.8
Synonyms	BDBM50260762 SCHEMBL1378898 (R)-4-(2-(3-(2-fluoro-6-(trifluoromethyl)benzyl)-5-(2-chlorophenyl)-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethylamino)butanoic acid
Inchi Key	WXJLFSUTNCMCGA-SANMLTNESA-N
Inchi ID	InChI=1S/C30H26ClF4N3O4/c31-24-12-5-4-10-20(24)21-16-37(17-22-23(30(33,34)35)11-6-13-25(22)32)29(42)38(28(21)41)18-26(19-8-2-1-3-9-19)36-15-7-14-27(39)40/h1-6,8-13,16,26,36H,7,14-15,17-18H2,(H,39,40)/t26-/m0/s1
PubChem CID	11467552
ChEMBL	CHEMBL450471
IUPHAR	N/A
BindingDB	50260762
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
384702	Gonadotropin-releasing hormone receptor	P30968	GNRHR	Homo sapiens (Human)	328
384703	Gonadotropin-releasing hormone receptor	P30969	Gnrhr	Rattus norvegicus (Rat)	327
384704	Gonadotropin-releasing hormone receptor	Q8SPZ1	GNRHR	Macaca mulatta (Rhesus macaque)	59

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