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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CGP-49823
Molecular formula	C31H33N3O
IUPAC name	[(2R,4S)-2-benzyl-4-(quinolin-4-ylmethylamino)piperidin-1-yl]-(3,5-dimethylphenyl)methanone
Molecular weight	463.625
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	6.0
Synonyms	{(2R,4S)-2-Benzyl-4-[(quinolin-4-ylmethyl)-amino]-piperidin-1-yl}-(3,5-dimethyl-phenyl)-methanone cgp49823 D0N1PA BDBM50287397 {(R)-2-Benzyl-4-[(quinolin-4-ylmethyl)-amino]-piperidin-1-yl}-(3,5-dimethyl-phenyl)-methanone 150705-88-7 SCHEMBL6904655 CHEMBL290364 [ Show all ]
Inchi Key	WQZUOBIIPDZRJP-WUFINQPMSA-N
Inchi ID	InChI=1S/C31H33N3O/c1-22-16-23(2)18-26(17-22)31(35)34-15-13-27(20-28(34)19-24-8-4-3-5-9-24)33-21-25-12-14-32-30-11-7-6-10-29(25)30/h3-12,14,16-18,27-28,33H,13,15,19-21H2,1-2H3/t27-,28+/m0/s1
PubChem CID	9869033
ChEMBL	CHEMBL290364
IUPHAR	N/A
BindingDB	50287397
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
380174	Neuromedin-K receptor	P29371	TACR3	Homo sapiens (Human)	465
380175	Substance-K receptor	P05363	TACR2	Bos taurus (Bovine)	384
380173	Substance-P receptor	P25103	TACR1	Homo sapiens (Human)	407

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