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GLASS

You can:

Check the GPCR table for details.
Go to the ligand list to see ligands that interacts with this GPCR.
Go to the individual ligand page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

GPCR

Name	Substance-K receptor
Species	Bos taurus (Bovine)
Gene	TACR2
Synonym	Neurokinin A receptor NK-2 receptor NK-2R SKR Tachykinin receptor 2
Disease	N/A for non-human GPCRs
Length	384
Amino acid sequence	MGACVVMTDINISSGLDSNATGITAFSMPGWQLALWTAAYLALVLVAVMGNATVIWIILAHQRMRTVTNYFIVNLALADLCMAAFNAAFNFVYASHNIWYFGRAFCYFQNLFPITAMFVSIYSMTAIAADRYMAIVHPFQPRLSAPGTRAVIAGIWLVALALAFPQCFYSTITTDEGATKCVVAWPEDSGGKMLLLYHLIVIALIYFLPLVVMFVAYSVIGLTLWRRSVPGHQAHGANLRHLQAKKKFVKTMVLVVVTFAICWLPYHLYFILGTFQEDIYCHKFIQQVYLALFWLAMSSTMYNPIIYCCLNHRFRSGFRLAFRCCPWVTPTEEDKMELTYTPSLSTRVNRCHTKEIFFMSGDVAPSEAVNGQAESPQAGVSTEP
UniProt	P05363
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4815
IUPHAR	N/A
DrugBank	N/A

Known ligands

You can:

Click GLASS IDs to check the association information.
Click ligand names to check details of the ligands.
Download a TSV version of all interaction information.
Download a SDF structure collection of all known ligands.

GLASS ID	Molecule	Formula	Molecular weight	H-bond acceptor / donor	XlogP	Lipinski's druglikeness
21973	L-Serine,N-[1-oxo-3-(2-pentylphenyl)propyl]-L-threonyl-(aE)-a,b-didehydro-N-methyltyrosyl-L-leucyl-D-phenylalanyl-L-allothreonyl-L-asparaginyl-,(7®1)-lactone	C54H72N8O13	1041.21	13 / 10	4.9	No
81432	CP 96345	C28H32N2O	412.577	3 / 1	5.4	No
112536	Substance K	C50H80N14O14S	1133.33	18 / 16	-4.8	No
130566	CHEMBL43912	C29H25Cl2N3O2	518.438	3 / 1	6.5	No
460458	Abt-418	C9H14N2O	166.224	3 / 0	1.2	Yes
165087	CHEMBL71397	C29H32Cl2N2O2	511.487	3 / 1	5.9	No
203502	CUMI-101	C19H27N5O3	373.457	6 / 0	1.8	Yes
259145	Saredutant	C31H35Cl2N3O2	552.54	3 / 1	5.9	No
259158	CHEMBL56835	C31H35Cl2N3O2	552.54	3 / 1	5.9	No
337796	CHEMBL295122	C31H33N3O	463.625	3 / 1	6.0	No
380169	CHEMBL297883	C31H33N3O	463.625	3 / 1	6.0	No
380175	CGP-49823	C31H33N3O	463.625	3 / 1	6.0	No
462527	CHEMBL372587	C34H39Cl2N3O5	640.602	6 / 1	5.7	No
462528	MDL-105212	C34H39Cl2N3O5	640.602	6 / 1	5.7	No
462585	A-85380	C9H12N2O	164.208	3 / 1	0.6	Yes
401501	CHEMBL295425	C31H25F6N3O3	601.549	9 / 2	5.8	No

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