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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Substance-K receptor
Species	Bos taurus (Bovine)
Gene	TACR2
Synonym	Neurokinin A receptor NK-2 receptor NK-2R SKR Tachykinin receptor 2
Disease	N/A for non-human GPCRs
Length	384
Amino acid sequence	MGACVVMTDINISSGLDSNATGITAFSMPGWQLALWTAAYLALVLVAVMGNATVIWIILAHQRMRTVTNYFIVNLALADLCMAAFNAAFNFVYASHNIWYFGRAFCYFQNLFPITAMFVSIYSMTAIAADRYMAIVHPFQPRLSAPGTRAVIAGIWLVALALAFPQCFYSTITTDEGATKCVVAWPEDSGGKMLLLYHLIVIALIYFLPLVVMFVAYSVIGLTLWRRSVPGHQAHGANLRHLQAKKKFVKTMVLVVVTFAICWLPYHLYFILGTFQEDIYCHKFIQQVYLALFWLAMSSTMYNPIIYCCLNHRFRSGFRLAFRCCPWVTPTEEDKMELTYTPSLSTRVNRCHTKEIFFMSGDVAPSEAVNGQAESPQAGVSTEP
UniProt	P05363
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4815
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL295425
Molecular formula	C31H25F6N3O3
IUPAC name	N-[(2R,4S)-2-benzyl-1-[3,5-bis(trifluoromethyl)benzoyl]piperidin-4-yl]-2-oxo-1H-quinoline-4-carboxamide
Molecular weight	601.549
Hydrogen bond acceptor	9
Hydrogen bond donor	2
XlogP	5.8
Synonyms	2-Hydroxy-quinoline-4-carboxylic acid [(2R,4S)-2-benzyl-1-(3,5-bis-trifluoromethyl-benzoyl)-piperidin-4-yl]-amide BDBM50287416
Inchi Key	XUVYYIIVCVDGFW-XZOQPEGZSA-N
Inchi ID	InChI=1S/C31H25F6N3O3/c32-30(33,34)20-13-19(14-21(15-20)31(35,36)37)29(43)40-11-10-22(16-23(40)12-18-6-2-1-3-7-18)38-28(42)25-17-27(41)39-26-9-5-4-8-24(25)26/h1-9,13-15,17,22-23H,10-12,16H2,(H,38,42)(H,39,41)/t22-,23+/m0/s1
PubChem CID	44289197
ChEMBL	CHEMBL295425
IUPHAR	N/A
BindingDB	50287416
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Inhibition	28.0 %	Bioorg. Med. Chem. Lett., (1996) 6:14:1623	ChEMBL

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