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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Tilozepine
Molecular formula	C17H18ClN3S
IUPAC name	7-chloro-4-(4-methylpiperazin-1-yl)-10H-thieno[3,2-c][1]benzazepine
Molecular weight	331.862
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	3.2
Synonyms	NSC_172286 7-chloro-4-(4-methylpiperazin-1-yl)-10H-thieno[3,2-c][1]benzazepine BDBM81985 Tilozepina 10H-Thieno(3,2-c)(1)benzazepine, 7-chloro-4-(4-methyl-1-piperazinyl)- DTXSID30195074 UNII-3RG8Q831DX 7-chloro-10-(4-methyl-piperazin-1-yl)-4H-3-thia-9-aza-benzo(f)azulene NT 104-252 CAS_42239-60-1 3RG8Q831DX L001129 ZINC31490523 7-chloro-4-(4-methyl-1-piperazinyl)-10H-Thieno(3,2-c)(1)benzazepine AC1L58W0 SCHEMBL2110610 CHEMBL2105484 Tilozepine [INN] 42239-60-1 [ Show all ]
Inchi Key	SKASXEDXLXEXKN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H18ClN3S/c1-20-5-7-21(8-6-20)17-14-4-9-22-16(14)10-12-2-3-13(18)11-15(12)19-17/h2-4,9,11H,5-8,10H2,1H3
PubChem CID	172286
ChEMBL	N/A
IUPHAR	N/A
BindingDB	81985
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
316286	D(1A) dopamine receptor	Q61616	Drd1	Mus musculus (Mouse)	446
556739	D(2) dopamine receptor	P61168	Drd2	Mus musculus (Mouse)	444

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