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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL117288
Molecular formula	C17H20ClN5O
IUPAC name	2-[3-[2-(3-chloroanilino)ethylamino]propyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Molecular weight	345.831
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	2.5
Synonyms	2-[3-[2-(3-Chloroanilino)ethylamino]propyl]-1,2,4-triazolo[4,3-a]pyridine-3(2H)-one
Inchi Key	SGXXTUPUUQQXFD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H20ClN5O/c18-14-5-3-6-15(13-14)20-10-9-19-8-4-12-23-17(24)22-11-2-1-7-16(22)21-23/h1-3,5-7,11,13,19-20H,4,8-10,12H2
PubChem CID	10807497
ChEMBL	CHEMBL117288
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
314077	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
314076	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
454164	Histamine H1 receptor	P30546	HRH1	Bos taurus (Bovine)	491

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