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GLASS

You can:

Check the GPCR table for details.
Go to the ligand list to see ligands that interacts with this GPCR.
Go to the individual ligand page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

GPCR

Name	Histamine H1 receptor
Species	Bos taurus (Bovine)
Gene	HRH1
Synonym	H1R HH1R
Disease	N/A for non-human GPCRs
Length	491
Amino acid sequence	MTCPNSSCVFEDKMCQGNKTAPANDAQLTPLVVVLSTISLVTVGLNLLVLYAVRSERKLHTVGNLYIVSLSVADLIVGVVVMPMNILYLLMSRWSLGRPLCLFWLSMDYVASTASIFSVFILCIDRYRSVQQPLKYLRYRTKTRASITILAAWFLSFLWIIPILGWRHFQPKTPEPREDKCETDFYNVTWFKVMTAIINFYLPTLLMLWFYAKIYKAVRQHCQHRELINGSFPSFSDMKMKPENLQVGAKKPGKESPWEVLKRKPKDTGGGPVLKPPSQEPKEVTSPGVFSQEKEEKDGELGKFYCFPLDTVQAQPEAEGSGRGYATINQSQNQLEMGEQGLSMPGAKEALEDQILGDSQSFSRTDSDTPAEPAPAKGKSRSESSTGLEYIKFTWKRLRSHSRQYVSGLHMNRERKAAKQLGFIMAAFIICWIPYFIFFMVIAFCESCCNQHVHMFTIWLGYINSTLNPLIYPLCNENFKKTFKKILHIRS
UniProt	P30546
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3573
IUPHAR	N/A
DrugBank	N/A

Known ligands

You can:

Click GLASS IDs to check the association information.
Click ligand names to check details of the ligands.
Download a TSV version of all interaction information.
Download a SDF structure collection of all known ligands.

GLASS ID	Molecule	Formula	Molecular weight	H-bond acceptor / donor	XlogP	Lipinski's druglikeness
58163	CHEMBL325250	C19H20ClN5O2	385.852	4 / 0	2.1	Yes
77995	CHEMBL325489	C20H24ClN5O	385.896	4 / 0	3.3	Yes
149366	CHEMBL116977	C20H24ClN5O	385.896	4 / 0	3.3	Yes
447675	CHEMBL117476	C18H22ClN5O	359.858	4 / 1	2.6	Yes
173792	CHEMBL117507	C20H24ClN5O	385.896	4 / 0	3.3	Yes
192256	CHEMBL115382	C21H26ClN5O	399.923	4 / 0	3.7	Yes
203483	CUMI-101	C19H27N5O3	373.457	6 / 0	1.8	Yes
229083	CHEMBL117027	C22H28ClN5O	413.95	4 / 0	3.9	Yes
234455	CHEMBL118691	C21H26ClN5O	399.923	4 / 0	3.8	Yes
248566	CHEMBL323688	C20H24ClN5O	385.896	4 / 0	3.3	Yes
259886	trazodone	C19H22ClN5O	371.869	4 / 0	2.8	Yes
270667	[2-(1-hydroxycyclohexyl)-2-(4-hydroxyphenyl)ethyl]dimethylammonium 3-carboxypropanoate monohydrate	C20H33NO7	399.484	7 / 5	N/A	N/A
452706	CHEMBL115418	C18H22ClN5O	359.858	4 / 1	2.9	Yes
454164	CHEMBL117288	C17H20ClN5O	345.831	4 / 2	2.5	Yes
332927	CHEMBL117439	C20H22ClN5O2	399.879	4 / 0	2.5	Yes
377926	CHEMBL81649	C21H27N3O3S	401.525	6 / 1	2.2	Yes

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