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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	PK 11195
Molecular formula	C21H21ClN2O
IUPAC name	N-butan-2-yl-1-(2-chlorophenyl)-N-methylisoquinoline-3-carboxamide
Molecular weight	352.862
Hydrogen bond acceptor	2
Hydrogen bond donor	0
XlogP	5.5
Synonyms	SCHEMBL117124 1-(2-Chlorophenyl)-N-methyl-N-(1-methylpropyl) AC1L1B9T BRD-A41451487-001-04-7 CHEMBL481537 DTXSID7041097 HMS3266H15 MLS000028483 NCGC00015205-05 NCGC00260883-01 SR-01000076240-1 1-(2-chlorophenyl)-N-methyl-N-(sec-butyl)isoquinoline-3-carboxamide BDBM22032 CAS-85532-75-8 D03NOO FT-0724157 Interferon alfa (IFN-alpha) N-(butan-2-yl)-1-(2-chlorophenyl)-N-methylisoquinoline-3-carboxamide NCGC00015205-08 Tox21_500198 85340-56-3 BPBio1_001278 CHEMBL15313 DSSTox_GSID_41097 HMS2234C05 LS-85394 NCGC00015205-03 NCGC00024720-04 PK11195 SMR000058427 1-(2-Chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide AKOS024458600 BRN 4264456 CS-0015789 EU-0100198 HMS3372J02 MLS006010699 NCGC00015205-06 PDSP1_000637 SR-01000076240-3 Biomol-NT_000287 CCG-204293 D0VN4K GL4857 Lopac0_000198 N-butan-2-yl-1-(2-chlorophenyl)-N-methylisoquinoline-3-carboxamide NCGC00024720-02 PK-11195 RP 52028 [3H]PK 11195 85532-75-8 BRD-A41451487-001-01-3 DSSTox_RID_79625 HMS3260H17 MFCD00069334 NCGC00015205-04 NCGC00254354-01 SR-01000076240 1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)isoquinoline-3-carboxamide AOB5180 C 0424 CTK8G2452 EX-A2448 HY-19567 MolPort-003-940-598 NCGC00015205-07 PDSP2_000632 Tox21_300620 3-Isoquinolinecarboxamide, 1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)- BN0423 CHEBI:73290 DSSTox_CID_21097 GTPL8703 LP00198 N-sec-butyl-1-(2-chlorophenyl)-N-methylisoquinoline-3-carboxamide NCGC00024720-03 PK-11195; RP-52028 [ Show all ]
Inchi Key	RAVIZVQZGXBOQO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H21ClN2O/c1-4-14(2)24(3)21(25)19-13-15-9-5-6-10-16(15)20(23-19)17-11-7-8-12-18(17)22/h5-14H,4H2,1-3H3
PubChem CID	1345
ChEMBL	CHEMBL481537
IUPHAR	N/A
BindingDB	22032
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
556613	Gamma-aminobutyric acid type B receptor subunit 1	Q9Z0U4	Gabbr1	Rattus norvegicus (Rat)	991
291710	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371
291709	Thyrotropin-releasing hormone receptor	P21761	Trhr	Mus musculus (Mouse)	393

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