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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1775176
Molecular formula	C23H29N5O5S
IUPAC name	2,2-dimethylpropyl 4-[1-(4-methylsulfonylphenyl)pyrazolo[3,4-d]pyrimidin-4-yl]oxypiperidine-1-carboxylate
Molecular weight	487.575
Hydrogen bond acceptor	8
Hydrogen bond donor	0
XlogP	3.6
Synonyms	142942-EP2292620A2 SCHEMBL390325 BDBM50343456 142942-EP2287165A2 neopentyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate 4-[1-(4-Methanesulfonyl-phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy]-piperidine-1-carboxylic acid 2,2-dimethyl-propyl ester 142942-EP2287166A2 QZMJKQWYWOFUDT-UHFFFAOYSA-N [ Show all ]
Inchi Key	QZMJKQWYWOFUDT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H29N5O5S/c1-23(2,3)14-32-22(29)27-11-9-17(10-12-27)33-21-19-13-26-28(20(19)24-15-25-21)16-5-7-18(8-6-16)34(4,30)31/h5-8,13,15,17H,9-12,14H2,1-4H3
PubChem CID	21897675
ChEMBL	CHEMBL1775176
IUPHAR	N/A
BindingDB	50343456
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
290605	Glucose-dependent insulinotropic receptor	Q8TDV5	GPR119	Homo sapiens (Human)	335
290606	Glucose-dependent insulinotropic receptor	Q7TQN8	Gpr119	Rattus norvegicus (Rat)	468

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