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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL183706
Molecular formula	C26H32N2O4
IUPAC name	2-[2-[4-[1-(2-ethoxyethyl)indol-3-yl]piperidin-1-yl]ethoxy]benzoic acid
Molecular weight	436.552
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	1.6
Synonyms	2-(2-{4-[1-(2-Ethoxy-ethyl)-1H-indol-3-yl]-piperidin-1-yl}-ethoxy)-benzoic acid BDBM50156867 QSOACFIAXDGTQW-UHFFFAOYSA-N 2-(2-{4-[1-(2-ethoxyethyl)-1H-indol-3-yl]piperidin-1-yl}ethoxy)benzoic acid SCHEMBL6776305
Inchi Key	QSOACFIAXDGTQW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H32N2O4/c1-2-31-17-16-28-19-23(21-7-3-5-9-24(21)28)20-11-13-27(14-12-20)15-18-32-25-10-6-4-8-22(25)26(29)30/h3-10,19-20H,2,11-18H2,1H3,(H,29,30)
PubChem CID	11282005
ChEMBL	CHEMBL183706
IUPHAR	N/A
BindingDB	50156867
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
285865	Histamine H1 receptor	P70174	Hrh1	Mus musculus (Mouse)	488
285866	Histamine H1 receptor	P31389	HRH1	Cavia porcellus (Guinea pig)	488
285868	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359
285867	Histamine H3 receptor	P58406	Hrh3	Mus musculus (Mouse)	445

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