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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL376781
Molecular formula	C23H24FN3OS2
IUPAC name	1-[1-[(3-fluorophenyl)methyl]piperidin-4-yl]-4,4-dithiophen-2-ylimidazolidin-2-one
Molecular weight	441.583
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.0
Synonyms	BDBM50207990 SCHEMBL13945682 3-(1-(3-fluorobenzyl)-piperidin-4-yl)-5,5-di-(2-thienyl)-imidazolidin-2-one
Inchi Key	PZNWDUWKLZHRGR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H24FN3OS2/c24-18-5-1-4-17(14-18)15-26-10-8-19(9-11-26)27-16-23(25-22(27)28,20-6-2-12-29-20)21-7-3-13-30-21/h1-7,12-14,19H,8-11,15-16H2,(H,25,28)
PubChem CID	16124707
ChEMBL	CHEMBL376781
IUPHAR	N/A
BindingDB	50207990
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
272840	Muscarinic acetylcholine receptor M2	P08172	CHRM2	Homo sapiens (Human)	466
272839	Muscarinic acetylcholine receptor M3	P20309	CHRM3	Homo sapiens (Human)	590
272841	Muscarinic acetylcholine receptor M3	Q9ERZ3	Chrm3	Mus musculus (Mouse)	589

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