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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL218710
Molecular formula	C7H9NO5S
IUPAC name	(1R,4S,5S,6S)-4-amino-2-oxo-2lambda4-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid
Molecular weight	219.211
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	-5.1
Synonyms	BDBM50202406 LS-194071 (-)-(1R,2S,4S,5S,6S)-4-amino-2-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid 2-oxide LY-404040 (+)-(1R,2R,4S,5S,6S)-4-amino-2-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid 2-oxide [(1beta,5beta)-4-Amino-2-thiabicyclo[3.1.0]hexane-4beta,6beta-dicarboxylic acid]2-oxide (-)-(1R,2R,4S,5S,6S)-4-amino-2-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid 2-oxide [ Show all ]
Inchi Key	PYCDNJSXQRXRFH-BPOMBSSQSA-N
Inchi ID	InChI=1S/C7H9NO5S/c8-7(6(11)12)1-14(13)4-2(3(4)7)5(9)10/h2-4H,1,8H2,(H,9,10)(H,11,12)/t2-,3-,4+,7+,14?/m1/s1
PubChem CID	10353365
ChEMBL	CHEMBL218710
IUPHAR	N/A
BindingDB	50202406
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
271865	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
271863	Metabotropic glutamate receptor 3	Q14832	GRM3	Homo sapiens (Human)	879
271864	Metabotropic glutamate receptor 8	O00222	GRM8	Homo sapiens (Human)	908

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